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Nora Pashayan

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Articles 154
Citations 4027
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Recent Articles
1.
Ip S, Harrison H, Usher-Smith J, Barclay M, Tyrer J, Dennis J, et al.
BMJ Oncol . 2025 Mar; 4(1):e000336. PMID: 40046831
Objectives: To quantify the contributions of polygenic scores, primary care records (presenting symptoms, medical history and common blood tests) and lifestyle factors, for short-term risk prediction of colorectal cancer (CRC)...
2.
Callender T, Payne K, Pashayan N, Mackie A
BMJ . 2025 Feb; 388:e081098. PMID: 40000108
No abstract available.
3.
Moore C, Frangou E, McCartan N, Santaolalla A, Kopcke D, Brembilla G, et al.
BMJ Oncol . 2025 Jan; 2(1):e000057. PMID: 39886504
Objective: In men with a raised prostate-specific antigen (PSA), MRI increases the detection of clinically significant cancer and reduces overdiagnosis, with fewer biopsies. MRI as a screening tool has not...
4.
Barclay M, Renzi C, Harrison H, Torralbo A, White B, Ip S, et al.
BMJ Oncol . 2025 Jan; 3(1):e000500. PMID: 39886176
Objectives: Assessment of age, sex and smoking-specific risk of cancer diagnosis and non-cancer mortality following primary care consultation for 15 new-onset symptoms. Methods And Analysis: Data on patients aged 30-99...
5.
McAteer M, McGowan D, Cook G, Leung H, Ng T, OConnor J, et al.
BMC Med . 2025 Jan; 23(1):37. PMID: 39849494
Background: The clinical translation of positron emission tomography (PET) radiotracers for cancer management presents complex challenges. We have developed consensus-based recommendations for preclinical and clinical assessment of novel and established...
6.
Srinivasan S, Kryza T, Bock N, Tse B, Sokolowski K, Janaththani P, et al.
Nat Commun . 2024 Nov; 15(1):9587. PMID: 39505858
Genetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA)...
7.
Anderson A, Visintin C, Antoniou A, Pashayan N, Gilbert F, Hackshaw A, et al.
BMC Proc . 2024 Oct; 18(Suppl 19):22. PMID: 39444025
Population screening for breast cancer (BC) is currently offered in the UK for women aged 50 to 71 with the aim of reducing mortality. There is additional screening within the...
8.
Marsden T, Attard G, Punwani S, Giganti F, Freeman A, Haider A, et al.
PLoS One . 2024 Oct; 19(10):e0295994. PMID: 39418289
Introduction: RECONCILE (ClinicalTrials.gov:NCT04340245) will identify molecular and radiomic markers associated with clinical progression and radiological progression events in a cohort of localised, newly diagnosed Gleason 3 + 4 tumours. Molecular...
9.
Yang X, Wu Y, Ficorella L, Wilcox N, Dennis J, Tyrer J, et al.
Br J Cancer . 2024 Sep; 131(9):1473-1479. PMID: 39294438
Background: The clinical validity of the multifactorial BOADICEA model for epithelial tubo-ovarian cancer (EOC) risk prediction has not been assessed in a large sample size or over a longer term....
10.
Hall R, Bancroft E, Pashayan N, Kote-Jarai Z, Eeles R
J Med Genet . 2024 Aug; 61(10):915-926. PMID: 39137963
Prostate cancer (PrCa) is a largely heritable and polygenic disease. It is the most common cancer in people with prostates (PwPs) in Europe and the USA, including in PwPs of...