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Nobuhiro Nishiyama

Explore the profile of Nobuhiro Nishiyama including associated specialties, affiliations and a list of published articles. Areas
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Articles 269
Citations 5056
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Recent Articles
1.
Voon Y, Guo H, Kanamori K, Ogiyama T, Chaya H, Morita K, et al.
Biomacromolecules . 2025 Mar; PMID: 40053609
L-type amino acid transporter 1 (LAT1), which takes up neutral amino acids such as tyrosine, is overexpressed on various cancer cells, and many researchers have developed LAT1-targeting drug delivery systems...
2.
Honda Y, Nagao S, Kinoh H, Liu X, Matsudaira N, Dirisala A, et al.
ACS Nano . 2025 Feb; 19(8):7690-7706. PMID: 39900524
Adeno-associated viruses (AAVs) are increasingly used in gene therapy to treat debilitating genetic diseases. However, systemically administered AAVs are often inactivated by neutralizing antibodies (NAbs), and high-dose administration of AAVs...
3.
Shirai K, Saito Y, Satoh K, Tomizawa A, Nonami N, Maeda S, et al.
Audiol Neurootol . 2025 Jan; :1-12. PMID: 39848237
Introduction: Despite improved hearing, children who receive cochlear implants (CIs) at a later age encounter difficulties in adapting to society, exposing them to psychological and social risks. This study contributes...
4.
Konarita K, Kanamori K, Suzuki M, Tokura D, Tanaka S, Honda Y, et al.
J Control Release . 2024 Nov; 377:385-396. PMID: 39532208
Since the discovery of d-amino acids, they have been considered inactive and have not been used as potent drugs. Here, we report that simple mixing with poly(vinyl alcohol) (PVA) unleashed...
5.
Toyoda M, Miura Y, Kobayashi M, Tsuda M, Nomoto T, Honda Y, et al.
Biomacromolecules . 2024 Oct; 25(12):7788-7798. PMID: 39481019
Polyzwitterions that show the alternation of net charge in response to external stimuli have attracted great attention as a new class of surface-polymers on nanomedicines. However, the correlation between their...
6.
Tokura D, Konarita K, Suzuki M, Ogata K, Honda Y, Miura Y, et al.
J Control Release . 2024 Jun; 371:445-454. PMID: 38844180
In boron neutron capture therapy (BNCT), boron drugs should exhibit high intratumoral boron concentrations during neutron irradiation, while being cleared from the blood and normal organs. However, it is usually...
7.
Homma K, Miura Y, Kobayashi M, Chintrakulchai W, Toyoda M, Ogi K, et al.
Sci Technol Adv Mater . 2024 Apr; 25(1):2338785. PMID: 38646148
Lipid nanoparticles (LNPs) coated with functional and biocompatible polymers have been widely used as carriers to deliver oligonucleotide and messenger RNA therapeutics to treat diseases. Poly(ethylene glycol) (PEG) is a...
8.
Sonobe R, Yang P, Suzuki M, Shinjo K, Iijima K, Nishiyama N, et al.
Cancer Sci . 2024 Apr; 115(6):1910-1923. PMID: 38558246
Chemoresistance is a major cause of high mortality and poor survival in patients with ovarian cancer (OVCA). Understanding the mechanisms of chemoresistance is urgently required to develop effective therapeutic approaches...
9.
Nakao M, Matsui M, Kim K, Nishiyama N, Grainger D, Okano T, et al.
Stem Cell Res Ther . 2023 Dec; 14(1):352. PMID: 38072920
Background: Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) sheets have recently attracted attention as an alternative approach to injected cell suspensions for stem cell therapy. However, cell engraftment and cytokine...
10.
Gao S, Miura Y, Sumiyoshi A, Ohno S, Ogata K, Nomoto T, et al.
Adv Sci (Weinh) . 2023 Nov; 11(7):e2304171. PMID: 38030413
Nano-sized contrast agents (NCAs) hold potential for highly specific tumor contrast enhancement during magnetic resonance imaging. Given the quantity of contrast agents loaded into a single nano-carrier and the anticipated...