Niven R Narain
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Explore the profile of Niven R Narain including associated specialties, affiliations and a list of published articles.
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79
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1873
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Recent Articles
1.
Lee D, Ta L, Mukherjee P, Duraj T, Domin M, Greenwood B, et al.
ASN Neuro
. 2024 Dec;
16(1):2422268.
PMID: 39621724
Energy is necessary for tumor cell viability and growth. Aerobic glucose-driven lactic acid fermentation is a common metabolic phenotype seen in most cancers including malignant gliomas. This metabolic phenotype is...
2.
Dreyfuss J, Djordjilovic V, Pan H, Bussberg V, MacDonald A, Narain N, et al.
Commun Biol
. 2024 Aug;
7(1):996.
PMID: 39143411
Activating brown adipose tissue (BAT) improves systemic metabolism, making it a promising target for metabolic syndrome. BAT is activated by 12,13-dihydroxy-9Z-octadecenoic acid (12,13-diHOME), which we previously identified to be inversely...
3.
Tsuji T, Tolstikov V, Zhang Y, Huang T, Camara H, Halpin M, et al.
Nat Commun
. 2024 Aug;
15(1):6768.
PMID: 39117652
Light is fundamental for biological life, with most mammals possessing light-sensing photoreceptors in various organs. Opsin3 is highly expressed in adipose tissue which has extensive communication with other organs, particularly...
4.
Kopell B, Kaji D, Liharska L, Vornholt E, Valentine A, Lund A, et al.
medRxiv
. 2024 May;
PMID: 38798344
The prefrontal cortex (PFC) is a region of the brain that in humans is involved in the production of higher-order functions such as cognition, emotion, perception, and behavior. Neurotransmission in...
5.
Peng K, Klotz A, Guven A, Kapadnis U, Ravipaty S, Tolstikov V, et al.
Sci Rep
. 2024 May;
14(1):10036.
PMID: 38693432
Parkinson's disease is a progressive neurodegenerative disorder in which loss of dopaminergic neurons in the substantia nigra results in a clinically heterogeneous group with variable motor and non-motor symptoms with...
6.
Chand N, Tekumalla P, Rosenberg M, Dobi A, Ali A, Miller G, et al.
Cancers (Basel)
. 2024 Feb;
16(4).
PMID: 38398103
Prostate cancer represents a significant health risk to aging men, in which diagnostic challenges to the identification of aggressive cancers remain unmet. Prostate cancer screening is driven by the prostate-specific...
7.
Hernandez-Saavedra D, Hinkley J, Baer L, Pinckard K, Vidal P, Nirengi S, et al.
iScience
. 2024 Feb;
27(3):109083.
PMID: 38361627
Exercise mediates tissue metabolic function through direct and indirect adaptations to acylcarnitine (AC) metabolism, but the exact mechanisms are unclear. We found that circulating medium-chain acylcarnitines (AC) (C12-C16) are lower...
8.
Ravasz D, Bui D, Nazarian S, Pallag G, Karnok N, Roberts J, et al.
Sci Rep
. 2024 Jan;
14(1):1729.
PMID: 38242919
Anoxia halts oxidative phosphorylation (OXPHOS) causing an accumulation of reduced compounds in the mitochondrial matrix which impedes dehydrogenases. By simultaneously measuring oxygen concentration, NADH autofluorescence, mitochondrial membrane potential and ubiquinone...
9.
Dreyfuss J, Djordjilovic V, Pan H, Bussberg V, MacDonald A, Narain N, et al.
bioRxiv
. 2023 Jul;
PMID: 37503007
Activating brown adipose tissue (BAT) improves systemic metabolism, making it a promising target for metabolic syndrome. BAT is activated by 12, 13-dihydroxy-9Z-octadecenoic acid (12, 13-diHOME), which we previously identified to...
10.
Hinkley J, Yu G, Standley R, Distefano G, Tolstikov V, Narain N, et al.
J Physiol
. 2023 Feb;
601(11):2165-2188.
PMID: 36814134
Exercise-induced perturbation of skeletal muscle metabolites is a probable mediator of long-term health benefits in older adults. Although specific metabolites have been identified to be impacted by age, physical activity...