Nitzan Gonen
Overview
Explore the profile of Nitzan Gonen including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
465
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0
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Recent Articles
1.
Ridnik M, Abberbock E, Alipov V, Lhermann S, Kaufman S, Lubman M, et al.
Nucleic Acids Res
. 2024 Mar;
52(10):5514-5528.
PMID: 38499491
Male development in mammals depends on the activity of the two SOX gene: Sry and Sox9, in the embryonic testis. As deletion of Enhancer 13 (Enh13) of the Sox9 gene...
2.
Stevant I, Gonen N, Poulat F
Front Cell Dev Biol
. 2024 Jan;
11:1327410.
PMID: 38283992
Gonadal sex determination in mice is a complex and dynamic process, which is crucial for the development of functional reproductive organs. The expression of genes involved in this process is...
3.
Stopel A, Lev C, Dahari S, Adibi O, Armon L, Gonen N
Int J Biol Sci
. 2024 Jan;
20(3):1024-1041.
PMID: 38250158
The testis is responsible for sperm production and androgen synthesis. Abnormalities in testis development and function lead to disorders of sex development and male infertility. Currently, no system exists for...
4.
Klutstein M, Gonen N
Mol Reprod Dev
. 2023 Nov;
90(12):785-803.
PMID: 37997675
The process of aging refers to physiological changes that occur to an organism as time progresses and involves changes to DNA, proteins, metabolism, cells, and organs. Like the rest of...
5.
Gonen N, Eozenou C, Mitter R, Elzaiat M, Stevant I, Aviram R, et al.
Sci Adv
. 2023 Jan;
9(1):eabn9793.
PMID: 36598988
During embryonic development, mutually antagonistic signaling cascades determine gonadal fate toward a testicular or ovarian identity. Errors in this process result in disorders of sex development (DSDs), characterized by discordance...
6.
Sreenivasan R, Gonen N, Sinclair A
Sex Dev
. 2022 Jun;
16(2-3):80-91.
PMID: 35760052
SOX genesare master regulatory genes controlling development and are fundamental to the establishment of sex determination in a multitude of organisms. The discovery of the master sex-determining gene SRY in...
7.
8.
Ridnik M, Schoenfelder S, Gonen N
Sex Dev
. 2021 Oct;
15(5-6):317-334.
PMID: 34710870
Sex determination is the process by which an initial bipotential gonad adopts either a testicular or ovarian cell fate. The inability to properly complete this process leads to a group...
9.
Eozenou C, Gonen N, Touzon M, Jorgensen A, Yatsenko S, Fusee L, et al.
Proc Natl Acad Sci U S A
. 2020 Jun;
117(24):13680-13688.
PMID: 32493750
Sex determination in mammals is governed by antagonistic interactions of two genetic pathways, imbalance in which may lead to disorders/differences of sex development (DSD) in human. Among 46,XX individuals with...
10.
Gonen N, Lovell-Badge R
Curr Top Dev Biol
. 2019 Apr;
134:223-252.
PMID: 30999977
The bipotential nature of cell types in the early developing gonad and the process of sex determination leading to either testis or ovary differentiation makes this an interesting system in...