Nityanand Bolshette
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Explore the profile of Nityanand Bolshette including associated specialties, affiliations and a list of published articles.
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212
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Recent Articles
1.
Protocol for monitoring intrapulmonary vasodilation in mice using contrast-enhanced echocardiography
Bolshette N, Bueno-Levy H, Asher G
STAR Protoc
. 2025 Feb;
6(1):103647.
PMID: 39982822
Monitoring intrapulmonary vasodilation in animal models is vital for understanding pulmonary vascular physiology and disease mechanisms. Here, we present a protocol for the real-time visualization and quantification of pulmonary microvascular...
2.
Dandavate V, Bolshette N, Van Drunen R, Manella G, Bueno-Levy H, Zerbib M, et al.
Cell Metab
. 2024 Aug;
36(9):2038-2053.e5.
PMID: 39106859
The transcriptional response to hypoxia is temporally regulated, yet the molecular underpinnings and physiological implications are unknown. We examined the roles of hepatic Bmal1 and Hif1α in the circadian response...
3.
Bolshette N, Ezagouri S, Dandavate V, Karavaeva I, Golik M, Wang H, et al.
PLoS Biol
. 2023 Nov;
21(11):e3002367.
PMID: 37967106
In mammals, O2 and CO2 levels are tightly regulated and are altered under various pathological conditions. While the molecular mechanisms that participate in O2 sensing are well characterized, little is...
4.
Bolshette N, Ibrahim H, Reinke H, Asher G
Nat Rev Gastroenterol Hepatol
. 2023 Jun;
20(11):695-707.
PMID: 37291279
A wide variety of liver functions are regulated daily by the liver circadian clock and via systemic circadian control by other organs and cells within the gastrointestinal tract as well...
5.
Manella G, Bolshette N, Golik M, Asher G
Proc Natl Acad Sci U S A
. 2022 Oct;
119(44):e2209933119.
PMID: 36279450
Circadian clocks are synchronized by external timing cues to align with one another and the environment. Various signaling pathways have been shown to independently reset the phase of the clock....
6.
Blazevits O, Bolshette N, Vecchio D, Guijarro A, Croci O, Campaner S, et al.
Int J Mol Sci
. 2020 Apr;
21(7).
PMID: 32225100
The circadian transcriptional network is based on a competition between transcriptional activator and repressor complexes regulating the rhythmic expression of clock-controlled genes. We show here that the MYC-associated factor X,...
7.
Manella G, Aviram R, Bolshette N, Muvkadi S, Golik M, Smith D, et al.
Proc Natl Acad Sci U S A
. 2019 Dec;
117(1):779-786.
PMID: 31848250
The occurrence and sequelae of disorders that lead to hypoxic spells such as asthma, chronic obstructive pulmonary disease, and obstructive sleep apnea (OSA) exhibit daily variance. This prompted us to...
8.
Pardeshi R, Bolshette N, Gadhave K, Arfeen M, Ahmed S, Jamwal R, et al.
Front Pharmacol
. 2019 May;
10:288.
PMID: 31068802
Diabetes is a risk factor for Alzheimer's disease and it is associated with significant memory loss. In the present study, we hypothesized that the soluble epoxide hydrolase (sEH) inhibitor N-[1-(1-oxopropyl)-4-piperidinyl]-N'-[4-(trifluoromethoxy)phenyl)-urea...
9.
Pardeshi R, Bolshette N, Gadhave K, Ahire A, Ahmed S, Cassano T, et al.
Psychoneuroendocrinology
. 2017 Jun;
83:159-171.
PMID: 28624654
Alzheimer's disease (AD) is progressive neurodegenerative disorder characterized by accumulation of senile plaques, neurofibrillary tangles (NFT) and neurodegeneration. The diabetes mellitus (DM) is one of the risk factors for AD...
10.
Ahmed S, Mundhe N, Borgohain M, Chowdhury L, Kwatra M, Bolshette N, et al.
Inflammation
. 2016 Aug;
39(5):1783-97.
PMID: 27492452
Hyperglycaemia-mediated oxidative stress plays an imperative role in the progression of diabetic nephropathy. NF-kB is an important transcription factor in eukaryotes which regulates a diverse array of cellular process, including...