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Nisha Bte Mohd Rafiq

Explore the profile of Nisha Bte Mohd Rafiq including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 210
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Recent Articles
1.
Rafiq N, Grenci G, Lim C, Kozlov M, Jones G, Viasnoff V, et al.
Philos Trans R Soc Lond B Biol Sci . 2019 Aug; 374(1779):20180228. PMID: 31431172
Podosomes are a singular category of integrin-mediated adhesions important in the processes of cell migration, matrix degradation and cancer cell invasion. Despite a wealth of biochemical studies, the effects of...
2.
Rafiq N, Nishimura Y, Plotnikov S, Thiagarajan V, Zhang Z, Shi S, et al.
Nat Mater . 2019 Jun; 18(7):770. PMID: 31147615
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
3.
Rafiq N, Nishimura Y, Plotnikov S, Thiagarajan V, Zhang Z, Shi S, et al.
Nat Mater . 2019 May; 18(6):638-649. PMID: 31114072
The interrelationship between microtubules and the actin cytoskeleton in mechanoregulation of integrin-mediated adhesions is poorly understood. Here, we show that the effects of microtubules on two major types of cell-matrix...
4.
Rafiq N, Lieu Z, Jiang T, Yu C, Matsudaira P, Jones G, et al.
J Cell Biol . 2016 Dec; 216(1):181-197. PMID: 28007915
Podosomes represent a class of integrin-mediated cell-matrix adhesions formed by migrating and matrix-degrading cells. We demonstrate that in macrophage-like THP1 cells and fibroblasts stimulated to produce podosomes, down-regulation of the...
5.
Yu C, Rafiq N, Cao F, Zhou Y, Krishnasamy A, Biswas K, et al.
Nat Commun . 2015 Oct; 6:8672. PMID: 26507506
The turnover of integrin receptors is critical for cell migration and adhesion dynamics. Here we find that force development at integrins regulates adaptor protein recruitment and endocytosis. Using mobile RGD...
6.
Yu C, Rafiq N, Krishnasamy A, Hartman K, Jones G, Bershadsky A, et al.
Cell Rep . 2013 Dec; 5(5):1456-68. PMID: 24290759
Matrix-activated integrins can form different adhesion structures. We report that nontransformed fibroblasts develop podosome-like adhesions when spread on fluid Arg-Gly-Asp peptide (RGD)-lipid surfaces, whereas they habitually form focal adhesions on...
7.
Khan M, Wiradharma N, Beniah G, Rafiq N, Liu S, Au J, et al.
Curr Pharm Des . 2010 Jul; 16(21):2341-9. PMID: 20618155
DNA condensation, endosomal escape of DNA/polymeric complexes, and unpacking of DNA are the key steps in the process of non-viral gene delivery. Amongst these steps, currently the unpacking of the...