Nirosha J Murugan
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Explore the profile of Nirosha J Murugan including associated specialties, affiliations and a list of published articles.
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25
Citations
96
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Recent Articles
1.
Martel J, Rouleau N, Murugan N, Chin W, Ojcius D, Young J
Biomed J
. 2024 Dec;
:100824.
PMID: 39672328
The circadian rhythm controls a wide range of functions in the human body and is required for optimal health. Disruption of the circadian rhythm can produce inflammation and initiate or...
2.
Murugan N, Cariba S, Abeygunawardena S, Rouleau N, Payne S
Cell Mol Life Sci
. 2023 Dec;
81(1):9.
PMID: 38099951
Cells and tissues display a remarkable range of plasticity and tissue-patterning activities that are emergent of complex signaling dynamics within their microenvironments. These properties, which when operating normally guide embryogenesis...
3.
Rouleau N, Murugan N, Kaplan D
Nat Rev Bioeng
. 2023 Apr;
1(4):252-270.
PMID: 37064657
The functional complexity of the central nervous system (CNS) is unparalleled in living organisms. Its nested cells, circuits and networks encode memories, move bodies and generate experiences. Neural tissues can...
4.
Rosso C, Fera N, Murugan N, Voutsadakis I
J Diet Suppl
. 2022 Nov;
20(6):926-938.
PMID: 36373265
Vitamin D is an important regulator of bone health. In addition, as a ligand for a nuclear receptor expressed in breast cancer cells, vitamin D exerts neoplasia modulating effects in...
5.
Sperry M, Murugan N, Levin M
Methods Mol Biol
. 2022 Apr;
2450:51-67.
PMID: 35359302
Physarum polycephalum is a protist slime mould that exhibits a high degree of responsiveness to its environment through a complex network of tubes and cytoskeletal components that coordinate behavior across...
6.
Murugan N, Voutsadakis I
World J Gastrointest Oncol
. 2022 Feb;
14(1):38-54.
PMID: 35116102
Pancreatic adenocarcinoma is one of the most lethal cancers with rising incidence. Despite progress in its treatment, with the introduction of more effective chemotherapy regimens in the last decade, prognosis...
7.
Murugan N, Vigran H, Miller K, Golding A, Pham Q, Sperry M, et al.
Sci Adv
. 2022 Jan;
8(4):eabj2164.
PMID: 35080969
Limb regeneration is a frontier in biomedical science. Identifying triggers of innate morphogenetic responses in vivo to induce the growth of healthy patterned tissue would address the needs of millions...
8.
Murugan N, Kaltman D, Jin P, Chien M, Martinez R, Nguyen C, et al.
Adv Mater
. 2021 Jul;
33(34):e2008161.
PMID: 34263487
The unicellular protist Physarum polycephalum is an important emerging model for understanding how aneural organisms process information toward adaptive behavior. Here, it is revealed that Physarum can use mechanosensation to...
9.
Rouleau N, Murugan N, Kaplan D
Trends Cogn Sci
. 2021 Feb;
25(4):294-304.
PMID: 33546973
Bioengineered neural tissues help advance our understanding of neurodevelopment, regeneration, and neural disease; however, it remains unclear whether they can replicate higher-order functions including cognition. Building upon technical achievements in...
10.
Rouleau N, Murugan N, Rusk W, Koester C, Kaplan D
Ann Biomed Eng
. 2020 Jul;
48(8):2192-2203.
PMID: 32671625
The brain's extracellular matrix (ECM) is a dynamic protein-based scaffold within which neural networks can form, self-maintain, and re-model. When the brain incurs injuries, microscopic tissue tears and active ECM...