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Niranjan Nagarajan

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Articles 129
Citations 10462
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Recent Articles
1.
Pagac M, Davient B, Plado L, Lam H, Lee S, Ravikrishnan A, et al.
NPJ Biofilms Microbiomes . 2025 Jan; 11(1):13. PMID: 39800795
Sebaceous free fatty acids are metabolized by multiple skin microbes into bioactive lipid mediators termed oxylipins. This study investigated correlations between skin oxylipins and microbes on the superficial skin of...
2.
Ravikrishnan A, Wijaya I, Png E, Chng K, Ho E, Ng A, et al.
Nat Commun . 2024 Sep; 15(1):7751. PMID: 39237540
While rapid demographic changes in Asia are driving the incidence of chronic aging-related diseases, the limited availability of high-quality in vivo data hampers our ability to understand complex multi-factorial contributions,...
3.
Suphavilai C, Ko K, Lim K, Tan M, Boonsimma P, Chu J, et al.
Lancet Microbe . 2024 Jul; 5(9):100878. PMID: 39008997
Background: The emerging fungal pathogen Candida auris poses a serious threat to global public health due to its worldwide distribution, multidrug resistance, high transmissibility, propensity to cause outbreaks, and high...
4.
Shaw J, Gounot J, Chen H, Nagarajan N, Yu Y
Bioinformatics . 2024 Jun; 40(Suppl 1):i30-i38. PMID: 38940183
Summary: Shotgun metagenomics allows for direct analysis of microbial community genetics, but scalable computational methods for the recovery of bacterial strain genomes from microbiomes remains a key challenge. We introduce...
5.
Plum P, Hess T, Bertrand D, Morgenstern I, Velazquez Camacho O, Jonas C, et al.
Clin Transl Med . 2024 Jun; 14(6):e1723. PMID: 38877653
Background: Cholangiocarcinoma (CCA) is a fatal cancer of the bile duct with a poor prognosis owing to limited therapeutic options. The incidence of intrahepatic CCA (iCCA) is increasing worldwide, and...
6.
Hunt M, Hinrichs A, Anderson D, Karim L, Dearlove B, Knaggs J, et al.
bioRxiv . 2024 May; PMID: 38746185
The SARS-CoV-2 genome occupies a unique place in infection biology - it is the most highly sequenced genome on earth (making up over 20% of public sequencing datasets) with fine...
7.
Peres da Silva R, Suphavilai C, Nagarajan N
BMC Bioinformatics . 2024 Apr; 25(Suppl 1):153. PMID: 38627615
Background: With the rapid increase in throughput of long-read sequencing technologies, recent studies have explored their potential for taxonomic classification by using alignment-based approaches to reduce the impact of higher...
8.
Tan Y, Arros P, Berrios-Pasten C, Wijaya I, Chu W, Chen Y, et al.
ISME J . 2024 Mar; 18(1). PMID: 38547398
The hypervirulent lineages of Klebsiella pneumoniae (HvKp) cause invasive infections such as Klebsiella-liver abscess. Invasive infection often occurs after initial colonization of the host gastrointestinal tract by HvKp. Over 80%...
9.
Ding Y, Er S, Tan A, Gounot J, Saw W, Tan L, et al.
Microbiol Spectr . 2024 Mar; 12(4):e0396923. PMID: 38441466
Recently discovered (X) gene variants have provided new insights into microbial antibiotic resistance mechanisms and their potential consequences for public health. This study focused on detection, analysis, and characterization of...
10.
Tham E, Chia M, Riggioni C, Nagarajan N, Common J, Kong H
Allergy . 2024 Feb; 79(6):1470-1484. PMID: 38308490
The skin microbiome is an extensive community of bacteria, fungi, mites, viruses and archaea colonizing the skin. Fluctuations in the composition of the skin microbiome have been observed in atopic...