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Nir Maimon

Explore the profile of Nir Maimon including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 239
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Recent Articles
1.
Gupta N, Ochiai H, Hoshino Y, Klein S, Zustin J, Ramjiawan R, et al.
Cancers (Basel) . 2023 Feb; 15(4). PMID: 36831366
Radiotherapy (RT) is a standard treatment for patients with advanced prostate cancer (PCa). Previous preclinical studies showed that SDF1α/CXCR4 axis could mediate PCa metastasis (most often to the bones) and...
2.
Li H, Mei Y, Maimon N, Padera T, Baish J, Munn L
Sci Rep . 2019 Jul; 9(1):10649. PMID: 31337769
The lymphatic system contains intraluminal leaflet valves that function to bias lymph flow back towards the heart. These valves are present in the collecting lymphatic vessels, which generally have lymphatic...
3.
Chen J, Landegger L, Sun Y, Ren J, Maimon N, Wu L, et al.
Nat Protoc . 2019 Jan; 14(2):541-555. PMID: 30617350
Neurofibromatosis type II (NF2) is a disease that lacks effective therapies. NF2 is characterized by bilateral vestibular schwannomas (VSs) that cause progressive and debilitating hearing loss, leading to social isolation...
4.
Kozin S, Maimon N, Wang R, Gupta N, Munn L, Jain R, et al.
Oncotarget . 2018 Jan; 8(65):108292-108302. PMID: 29312532
SLPI has been implicated in the progression and metastasis of certain cancers. However, the effects of SLPI seem to be tumor-specific and the mechanisms remain poorly defined. Here, we demonstrate...
5.
Bazou D, Maimon N, Gruionu G, Grahovac J, Seano G, Liu H, et al.
J Tissue Eng Regen Med . 2017 Jun; 12(1):e318-e322. PMID: 28568605
Our understanding of cancer progression or response to therapies would benefit from benchtop, tissue-level assays that preserve the biology and anatomy of human tumours ex vivo. We present a methodology...
6.
Bazou D, Maimon N, Gruionu G, Munn L
Integr Biol (Camb) . 2016 Oct; 8(12):1301-1311. PMID: 27787529
Testing the efficacy of cancer drugs requires functional assays that recapitulate the cell populations, anatomy and biological responses of human tumors. Although current animal models and in vitro cell culture...
7.
Rahbari N, Kedrin D, Incio J, Liu H, Ho W, Nia H, et al.
Sci Transl Med . 2016 Oct; 8(360):360ra135. PMID: 27733559
The survival benefit of anti-vascular endothelial growth factor (VEGF) therapy in metastatic colorectal cancer (mCRC) patients is limited to a few months because of acquired resistance. We show that anti-VEGF...
8.
Bazou D, Ng M, Song J, Chin S, Maimon N, Munn L
Sci Rep . 2016 Sep; 6:34046. PMID: 27669993
Angiogenesis requires the coordinated growth and migration of endothelial cells (ECs), with each EC residing in the vessel wall integrating local signals to determine whether to remain quiescent or undergo...
9.
Gruionu G, Bazou D, Maimon N, Onita-Lenco M, Gruionu L, Huang P, et al.
Lab Chip . 2016 Apr; 16(10):1840-51. PMID: 27128791
Recruitment of new blood vessels from the surrounding tissue is central to tumor progression and involves a fundamental transition of the normal, organized vasculature into a dense disarray of vessels...
10.
Sarelius I, Titus P, Maimon N, Okech W, Wilke-Mounts S, Brennan J, et al.
J Physiol . 2015 Dec; 594(3):687-97. PMID: 26661689
The local arteriolar dilatation produced by contraction of skeletal muscle is dependent upon multiple signalling mechanisms. In addition to the many metabolic signals that mediate this vasodilatation, we show here...