Ning Xu Landen
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Explore the profile of Ning Xu Landen including associated specialties, affiliations and a list of published articles.
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43
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1656
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Recent Articles
1.
Liu Z, Bian X, Luo L, Bjorklund A, Li L, Zhang L, et al.
Cell Stem Cell
. 2024 Dec;
32(3):479-498.e8.
PMID: 39729995
Wound healing is vital for human health, yet the details of cellular dynamics and coordination in human wound repair remain largely unexplored. To address this, we conducted single-cell multi-omics analyses...
2.
Bian X, Piipponen M, Liu Z, Luo L, Geara J, Chen Y, et al.
Nat Commun
. 2024 Oct;
15(1):9286.
PMID: 39468077
Radiotherapy (RT), a common cancer treatment, unintentionally harms surrounding tissues, including the skin, and hinders wound healing years after treatment. This study aims to understand the mechanisms behind these late-onset...
3.
Wang Q, Niu G, Liu Z, Toma M, Geara J, Bian X, et al.
Br J Dermatol
. 2024 Oct;
192(3):468-480.
PMID: 39422230
Background: Skin wound healing involves a complex gene expression programme that remains largely undiscovered in humans. Circular RNAs (circRNAs) and microRNAs (miRNAs) are key players in this process. Objectives: To...
4.
Li D, Liu Z, Zhang L, Bian X, Wu J, Li L, et al.
Nat Commun
. 2024 Oct;
15(1):8637.
PMID: 39366968
The cell transition from an inflammatory phase to a subsequent proliferative phase is crucial for wound healing, yet the driving mechanism remains unclear. By profiling lncRNA expression changes during human...
5.
Xiao Y, Zhang C, Liu X, Yang Y, Landen N, Zhang Z, et al.
Front Surg
. 2024 Mar;
11:1349135.
PMID: 38468869
Objectives: Re-epithelialization is an important physiological process for repairing skin barrier function during wound healing. It is primarily mediated by coordinated migration, proliferation, and differentiation of keratinocytes. Long noncoding RNAs...
6.
Almet A, Yuan H, Annusver K, Ramos R, Liu Y, Wiedemann J, et al.
J Invest Dermatol
. 2023 Aug;
143(9):1667-1677.
PMID: 37612031
Single-cell technologies have become essential to driving discovery in both basic and translational investigative dermatology. Despite the multitude of available datasets, a central reference atlas of normal human skin, which...
7.
Zhang L, Piipponen M, Liu Z, Li D, Bian X, Niu G, et al.
Cell Death Differ
. 2023 Mar;
30(5):1334-1348.
PMID: 36869179
After a skin injury, keratinocytes switch from a state of homeostasis to one of regeneration leading to the reconstruction of the epidermal barrier. The regulatory mechanism of gene expression underpinning...
8.
Liu Z, Zhang L, Toma M, Li D, Bian X, Pastar I, et al.
Elife
. 2022 Aug;
11.
PMID: 35942686
MicroRNAs (miR), as important epigenetic control factors, reportedly regulate wound repair. However, our insufficient knowledge of clinically relevant miRs hinders their potential therapeutic use. For this, we performed paired small...
9.
Konieczny P, Xing Y, Sidhu I, Subudhi I, Mansfield K, Hsieh B, et al.
Science
. 2022 Jun;
377(6602):eabg9302.
PMID: 35709248
Mammalian cells autonomously activate hypoxia-inducible transcription factors (HIFs) to ensure survival in low-oxygen environments. We report here that injury-induced hypoxia is insufficient to trigger HIF1α in damaged epithelium. Instead, multimodal...
10.
Toma M, Liu Z, Wang Q, Zhang L, Li D, Sommar P, et al.
J Invest Dermatol
. 2022 Apr;
142(10):2793-2804.e26.
PMID: 35429518
Venous ulcers (VUs) have complex and obscure pathogenicity, and effective VU therapies are still lacking. Circular RNAs (circRNAs) have emerged as powerful gene regulators with important roles in health and...