Nina Jahrling
Overview
Explore the profile of Nina Jahrling including associated specialties, affiliations and a list of published articles.
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23
Citations
1570
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Recent Articles
1.
Becker K, Saghafi S, Pende M, Sabdyusheva-Litschauer I, Hahn C, Foroughipour M, et al.
Sci Rep
. 2019 Nov;
9(1):17625.
PMID: 31772375
We developed a deconvolution software for light sheet microscopy that uses a theoretical point spread function, which we derived from a model of image formation in a light sheet microscope....
2.
Schelle J, Wegenast-Braun B, Fritschi S, Kaeser S, Jahrling N, Eicke D, et al.
Ann Neurol
. 2019 Jul;
86(4):561-571.
PMID: 31359452
Objective: Clinical trials targeting β-amyloid peptides (Aβ) for Alzheimer disease (AD) failed for arguable reasons that include selecting the wrong stages of AD pathophysiology or Aβ being the wrong target....
3.
Jahrling N, Becker K, Saghafi S, Dodt H
Methods Mol Biol
. 2017 Mar;
1563:33-49.
PMID: 28324600
Light-sheet microscopy is an effective technique in neuroscience, developmental biology, and cancer research for visualizing and analyzing cellular networks and whole organs in three dimensions. Because this technique requires specimens...
4.
Saghafi S, Becker K, Hahn C, Pende M, Jahrling N, Wanis M, et al.
Microsc Res Tech
. 2016 Dec;
81(9):929-935.
PMID: 28000307
Here, we present an optically optimized system for static ultramicroscopy imaging technique. The unit for generating an ultra-thin light sheet employs aspheric and meso-optical elements (meso-aspheric system). An analytical as...
5.
Bulantova J, Machacek T, Panska L, Krejci F, Karch J, Jahrling N, et al.
Micron
. 2016 Feb;
83:62-71.
PMID: 26897588
Migration of parasitic worms through the host tissues, which may occasionally result in fatal damage to the internal organs, represents one of the major risks associated with helminthoses. In order...
6.
Dodt H, Saghafi S, Becker K, Jahrling N, Hahn C, Pende M, et al.
Neurophotonics
. 2016 Jan;
2(4):041407.
PMID: 26730396
We present an overview of the ultramicroscopy technique we developed. Starting from developments 100 years ago, we designed a light sheet microscope and a chemical clearing to image complete mouse...
7.
Jahrling N, Becker K, Wegenast-Braun B, Grathwohl S, Jucker M, Dodt H
PLoS One
. 2015 May;
10(5):e0125418.
PMID: 26017149
Alzheimer´s disease (AD) is the most common neurodegenerative disorder. AD neuropathology is characterized by intracellular neurofibrillary tangles and extracellular β-amyloid deposits in the brain. To elucidate the complexity of AD...
8.
Becker K, Hahn C, Saghafi S, Jahrling N, Wanis M, Dodt H
PLoS One
. 2014 Dec;
9(12):e114149.
PMID: 25463047
Tissue clearing allows microscopy of large specimens as whole mouse brains or embryos. However, lipophilic tissue clearing agents as dibenzyl ether limit storage time of GFP-expressing samples to several days...
9.
Gewies A, Castineiras-Vilarino M, Ferch U, Jahrling N, Heinrich K, Hoeckendorf U, et al.
PLoS One
. 2013 Nov;
8(11):e81833.
PMID: 24278461
Members of the PRDM protein family have been shown to play important roles during embryonic development. Previous in vitro and in situ analyses indicated a function of Prdm6 in cells...
10.
Becker K, Jahrling N, Saghafi S, Dodt H
Cold Spring Harb Protoc
. 2013 Aug;
2013(8):704-13.
PMID: 23906921
Ultramicroscopy (UM) is a powerful imaging technique that achieves precise and accurate three-dimensional (3D) reconstructions of intact macroscopic specimens with micrometer resolution. It was developed for specimens in the size...