Nimesh Bhaskaran
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Explore the profile of Nimesh Bhaskaran including associated specialties, affiliations and a list of published articles.
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6
Citations
318
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Recent Articles
1.
Cepeda D, Ng H, Sharifi H, Mahmoudi S, Cerrato V, Fredlund E, et al.
EMBO Mol Med
. 2013 Jun;
5(7):1067-86.
PMID: 23776131
SCF (Skp1/Cul1/F-box) ubiquitin ligases act as master regulators of cellular homeostasis by targeting key proteins for ubiquitylation. Here, we identified a hitherto uncharacterized F-box protein, FBXO28 that controls MYC-dependent transcription...
2.
Bhaskaran N, van Drogen F, Ng H, Kumar R, Ekholm-Reed S, Peter M, et al.
Mol Cell Biol
. 2012 Oct;
33(1):85-97.
PMID: 23109421
Cyclin E1, an activator of cyclin-dependent kinase 2 (Cdk2) that promotes replicative functions, is normally expressed periodically within the mammalian cell cycle, peaking at the G(1)-S-phase transition. This periodicity is...
3.
Bhaskaran N, Lin K, Gautier A, Woksepp H, Hellman U, Souchelnytskyi S
Proteomics Clin Appl
. 2010 Dec;
3(1):68-77.
PMID: 21136936
Acquiring high proliferation rate is crucial for carcinogenic transformation of cells. We report here proteome profiling of human breast epithelial cells with low (184A1) and high (MCF10A) proliferation rates. We...
4.
Vashisht A, Zumbrennen K, Huang X, Powers D, Durazo A, Sun D, et al.
Science
. 2009 Sep;
326(5953):718-21.
PMID: 19762596
Eukaryotic cells require iron for survival and have developed regulatory mechanisms for maintaining appropriate intracellular iron concentrations. The degradation of iron regulatory protein 2 (IRP2) in iron-replete cells is a...
5.
Bhaskaran N, Souchelnytskyi S
Proteomics
. 2008 Sep;
8(21):4507-20.
PMID: 18821524
Transforming growth factor-beta (TGFbeta) is a key regulator of cell proliferation, death, migration, and differentiation. To explore mechanisms of TGFbeta action, we performed systemic analysis of functional dependencies between 153...
6.
Yin B, Kiyamova R, Chua R, Caballero O, Gout I, Gryshkova V, et al.
Cancer Immun
. 2008 Feb;
8:3.
PMID: 18251464
Mouse monoclonal antibody MX35 was developed against ovarian cancer. The antibody showed homogeneous reactivity with approximately 90% of human ovarian epithelial cancers and with a limited number of normal tissues...