Nils C Gauthier
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Explore the profile of Nils C Gauthier including associated specialties, affiliations and a list of published articles.
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39
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1848
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Recent Articles
1.
Bonilla-Quintana M, Ghisleni A, Gauthier N, Rangamani P
J Cell Sci
. 2025 Jan;
138(4).
PMID: 39838899
The plasma membrane and the underlying skeleton form a protective barrier for eukaryotic cells. The molecular players forming this complex composite material constantly rearrange under mechanical stress. One of those...
2.
Ghisleni A, Bonilla-Quintana M, Crestani M, Lavagnino Z, Galli C, Rangamani P, et al.
Nat Commun
. 2024 Jul;
15(1):5711.
PMID: 38977673
The cell cortex is a dynamic assembly formed by the plasma membrane and underlying cytoskeleton. As the main determinant of cell shape, the cortex ensures its integrity during passive and...
3.
Crestani M, Kakogiannos N, Iori S, Iannelli F, Dini T, Maderna C, et al.
Small Methods
. 2024 May;
8(12):e2400210.
PMID: 38747088
Glioblastomas exhibit remarkable heterogeneity at various levels, including motility modes and mechanoproperties that contribute to tumor resistance and recurrence. In a recent study using gridded micropatterns mimicking the brain vasculature,...
4.
Ghisleni A, Gauthier N
Curr Opin Cell Biol
. 2023 Dec;
86:102294.
PMID: 38101114
Over the past 25 years, membrane tension has emerged as a primary mechanical factor influencing cell behavior. Although supporting evidences are accumulating, the integration of this parameter in the lifecycle...
5.
Sadhu R, Barger S, Penic S, Iglic A, Krendel M, Gauthier N, et al.
Soft Matter
. 2022 Dec;
19(1):31-43.
PMID: 36472164
Phagocytosis is the process of engulfment and internalization of comparatively large particles by cells, and plays a central role in the functioning of our immune system. We study the process...
6.
Barger S, Vorselen D, Gauthier N, Theriot J, Krendel M
Mol Biol Cell
. 2022 Sep;
33(14):br24.
PMID: 36129777
Phagocytosis requires rapid remodeling of the actin cytoskeleton for extension of membrane protrusions and force generation to ultimately drive the engulfment of targets. The detailed mechanisms of phagocytosis have almost...
7.
Krendel M, Gauthier N
Curr Opin Cell Biol
. 2022 Jul;
77:102112.
PMID: 35820329
Cells ingest large particles, such as bacteria, viruses, or apoptotic cells, via the process of phagocytosis, which involves formation of an actin-rich structure known as the phagocytic cup. Phagocytic cup...
8.
Crestani M, Dini T, Gauthier N, Monzo P
STAR Protoc
. 2022 May;
3(2):101331.
PMID: 35496779
Glioblastoma (GBM) cells invade the brain by following linear structures like blood vessel walls and white matter tracts by using specific motility modes. In this protocol, we describe two micropatterning...
9.
Vorselen D, Barger S, Wang Y, Cai W, Theriot J, Gauthier N, et al.
Elife
. 2021 Oct;
10.
PMID: 34708690
Phagocytosis requires rapid actin reorganization and spatially controlled force generation to ingest targets ranging from pathogens to apoptotic cells. How actomyosin activity directs membrane extensions to engulf such diverse targets...
10.
Monzo P, Crestani M, Chong Y, Ghisleni A, Hennig K, Li Q, et al.
Dev Cell
. 2021 Sep;
56(20):2841-2855.e8.
PMID: 34559979
Glioblastoma are heterogeneous tumors composed of highly invasive and highly proliferative clones. Heterogeneity in invasiveness could emerge from discrete biophysical properties linked to specific molecular expression. We identified clones of...