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Nilesh Samani

Explore the profile of Nilesh Samani including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 3880
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Recent Articles
1.
Byars S, Prestes P, Suphapimol V, Takeuchi F, De Vries N, Maier M, et al.
Cardiovasc Res . 2024 Mar; 120(7):769-781. PMID: 38501595
Aims: Prevention of human hypertension is an important challenge and has been achieved in experimental models. Brief treatment with renin-angiotensin system (RAS) inhibitors permanently reduces the genetic hypertension of the...
2.
Al-Mutairi F, Al-Hussaini A, Marsh A, Samani N, McCann G, Adlam D, et al.
J Ultrasound . 2022 Jan; 25(3):585-589. PMID: 35032295
Background: Shear wave elastography (SWE) is emerging as a valuable clinical tool for a variety of conditions. The aim of this pilot study was to assess the potential of SWE...
3.
Hindy G, Dornbos P, Chaffin M, Liu D, Wang M, Selvaraj M, et al.
Am J Hum Genet . 2021 Dec; 109(1):81-96. PMID: 34932938
Large-scale gene sequencing studies for complex traits have the potential to identify causal genes with therapeutic implications. We performed gene-based association testing of blood lipid levels with rare (minor allele...
4.
Woolley R, Ceelen D, Ouwerkerk W, Tromp J, Figarska S, Anker S, et al.
Eur J Heart Fail . 2021 Mar; 23(6):983-991. PMID: 33651430
Aims: The lack of effective therapies for patients with heart failure with preserved ejection fraction (HFpEF) is often ascribed to the heterogeneity of patients with HFpEF. We aimed to identify...
5.
Dominiczak D, Samani N, Sudlow C, Sansom O, Davies D
QJM . 2019 Sep; 112(9):733-742. PMID: 31505684
No abstract available.
6.
Peloso G, Nomura A, Khera A, Chaffin M, Won H, Ardissino D, et al.
Circ Genom Precis Med . 2019 Apr; 12(5):e002376. PMID: 30939045
Background Familial hypobetalipoproteinemia is a genetic disorder caused by rare protein-truncating variants (PTV) in the gene encoding APOB (apolipoprotein B), the major protein component of LDL (low-density lipoprotein) and triglyceride-rich...
7.
Samani N
Eur Heart J . 2018 Oct; 39(39):3571-3573. PMID: 30321341
No abstract available.
8.
Liu C, Kraja A, Smith J, Brody J, Franceschini N, Bis J, et al.
Nat Genet . 2016 Sep; 48(10):1162-70. PMID: 27618448
Meta-analyses of association results for blood pressure using exome-centric single-variant and gene-based tests identified 31 new loci in a discovery stage among 146,562 individuals, with follow-up and meta-analysis in 180,726...
9.
Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, et al.
Nat Commun . 2016 May; 7:11385. PMID: 27150562
Signalling molecules and pathways that mediate crosstalk between various tumour cellular compartments in cancer metastasis remain largely unknown. We report a mechanism of the interaction between perivascular cells and tumour-associated...
10.
Zanoni P, Khetarpal S, Larach D, Hancock-Cerutti W, Millar J, Cuchel M, et al.
Science . 2016 Mar; 351(6278):1166-71. PMID: 26965621
Scavenger receptor BI (SR-BI) is the major receptor for high-density lipoprotein (HDL) cholesterol (HDL-C). In humans, high amounts of HDL-C in plasma are associated with a lower risk of coronary...