Nilakshee Bhattacharya
Overview
Explore the profile of Nilakshee Bhattacharya including associated specialties, affiliations and a list of published articles.
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20
Citations
416
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Recent Articles
1.
Bennett A, Hull J, Mietzsch M, Bhattacharya N, Chipman P, McKenna R
Viruses
. 2025 Jan;
16(12.
PMID: 39772173
are ssDNA plant viruses whose control has both economical and agricultural importance. Their capsids assemble into two distinct architectural forms: (i) a T = 1 icosahedral and (ii) a unique...
2.
Bennett A, Gargas J, Kansol A, Lewis J, Hsi J, Hull J, et al.
J Virol
. 2023 Jun;
97(7):e0177222.
PMID: 37310260
Adeno-associated virus (AAV) is a nonenveloped single-stranded DNA (ssDNA) icosahedral T=1 virus being developed as a vector for clinical gene delivery systems. Currently, there are approximately 160 AAV clinical trials,...
3.
Mietzsch M, Hull J, Makal V, Ybargollin A, Yu J, McKissock K, et al.
J Virol
. 2022 May;
96(11):e0033522.
PMID: 35532224
Adeno-associated viruses (AAVs) are being developed as clinical gene therapy vectors. One issue undermining their broad use in the clinical setting is the high prevalence of circulating antibodies in the...
4.
Penzes J, Chipman P, Bhattacharya N, Zeher A, Huang R, McKenna R, et al.
J Virol
. 2021 Jul;
95(19):e0084321.
PMID: 34260280
Adeno-associated viruses (AAVs) are small nonenveloped single-stranded DNA (ssDNA) viruses that are currently being developed as gene therapy biologics. After cell entry, AAVs traffic to the nucleus using the endo-lysosomal...
5.
Yu J, Mietzsch M, Singh A, Ybargollin A, Kailasan S, Chipman P, et al.
Viruses
. 2021 Mar;
13(2).
PMID: 33672786
Human bocavirus 1 (HBoV1) has gained attention as a gene delivery vector with its ability to infect polarized human airway epithelia and 5.5 kb genome packaging capacity. Gorilla bocavirus 1...
6.
Mietzsch M, Jose A, Chipman P, Bhattacharya N, Daneshparvar N, McKenna R, et al.
Viruses
. 2021 Jan;
13(1).
PMID: 33450892
The capsid structures of most Adeno-associated virus (AAV) serotypes, already assigned to an antigenic clade, have been previously determined. This study reports the remaining capsid structures of AAV7, AAV11, AAV12,...
7.
Mietzsch M, Smith J, Yu J, Banala V, Emmanuel S, Jose A, et al.
Mol Ther Methods Clin Dev
. 2020 Nov;
19:362-373.
PMID: 33145372
Affinity-based purification of adeno-associated virus (AAV) vectors has replaced density-based methods for vectors used in clinical settings. This method utilizes camelid single-domain antibodies recognizing AAV capsids. These include AVB Sepharose...
8.
Penzes J, Pham H, Chipman P, Bhattacharya N, McKenna R, Agbandje-Mckenna M, et al.
Proc Natl Acad Sci U S A
. 2020 Aug;
117(33):20211-20222.
PMID: 32747554
The giant tiger prawn () is a decapod crustacean widely reared for human consumption. Currently, viruses of two distinct lineages of parvoviruses (PVs, family ; subfamily ) infect penaeid shrimp....
9.
Mietzsch M, Barnes C, Hull J, Chipman P, Xie J, Bhattacharya N, et al.
J Virol
. 2019 Dec;
94(6).
PMID: 31826994
Adeno-associated viruses (AAVs) from clade E are often used as vectors in gene delivery applications. This clade includes rhesus isolate 10 (AAVrh.10) and 39 (AAVrh.39) which, unlike representative AAV8, are...
10.
Guenther C, Brun M, Bennett A, Ho M, Chen W, Zhu B, et al.
Mol Ther
. 2019 Feb;
27(3):611-622.
PMID: 30772143
Adeno-associated virus (AAV) has emerged as a promising gene delivery vector because of its non-pathogenicity, simple structure and genome, and low immunogenicity compared to other viruses. However, its adoption as...