Nikolay L Manuylov
Overview
Explore the profile of Nikolay L Manuylov including associated specialties, affiliations and a list of published articles.
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7
Citations
151
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Recent Articles
1.
Efimenko E, Padua M, Manuylov N, Fox S, Morse D, Tevosian S
Dev Biol
. 2013 Jun;
381(1):144-58.
PMID: 23769843
Sex determination in mammals requires interaction between the transcription factor GATA4 and its cofactor FOG2. We have recently described the function of both proteins in testis development beyond the sex...
2.
Manuylov N, Tevosian S
ScientificWorldJournal
. 2009 Jul;
9:575-87.
PMID: 19578715
Previous work by us and others has shown that the loss of interaction between GATA4 and FOG2 protein partners is embryonic lethal due to heart failure at embryonic day (E)...
3.
Tevosian S, Manuylov N
Dev Dyn
. 2008 Nov;
237(12):3672-80.
PMID: 18985752
The mammalian embryonic gonad is a unique organ primordium in that it can adopt two different developmental fates-namely, differentiate as either a testis or an ovary-with dramatic consequences for an...
4.
Manuylov N, Smagulova F, Leach L, Tevosian S
Development
. 2008 Oct;
135(22):3731-43.
PMID: 18927154
We have demonstrated previously that mammalian sexual differentiation requires both the GATA4 and FOG2 transcriptional regulators to assemble the functioning testis. Here we have determined that the sexual development of...
5.
Manuylov N, Manuylova E, Avdoshina V, Tevosian S
Genesis
. 2008 Sep;
46(9):441-6.
PMID: 18781631
We have previously identified Serdin1/Lrrc10 as a cardiac-specific message that is expressed early in murine heart development and encodes a novel leucine-rich protein. A high degree of evolutionary conservation with...
6.
Smagulova F, Manuylov N, Leach L, Tevosian S
BMC Dev Biol
. 2008 Jun;
8:67.
PMID: 18577233
Background: GATA4 and FOG2 proteins are required for normal cardiac development in mice. It has been proposed that GATA4/FOG2 transcription complex exercises its function through gene activation as well as...
7.
Manuylov N, Fujiwara Y, Adameyko I, Poulat F, Tevosian S
Dev Biol
. 2007 Jun;
307(2):356-67.
PMID: 17540364
We have previously established an in vivo requirement for GATA4 and FOG2 transcription factors in sexual differentiation. Fog2 null mouse fetuses or fetuses homozygous for a targeted mutation in Gata4...