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Nikolay Kaloyanov

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Articles 6
Citations 35
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Recent Articles
1.
Petkova-Parlapanska K, Stefanov I, Ananiev J, Georgiev T, Hadzhibozheva P, Petrova-Tacheva V, et al.
Pharmaceuticals (Basel) . 2025 Jan; 18(1). PMID: 39861148
Gentamicin (GM) administration is associated with decreased metabolism, increased oxidative stress, and induction of nephrotoxicity. L., containing flavonoids, anthocyanins, and phytosterols, possesses antioxidant and anti-inflammatory potential. The present study aimed...
2.
Anichina K, Kaloyanov N, Zasheva D, Rusew R, Nikolova R, Yancheva D, et al.
Molecules . 2024 Feb; 29(3). PMID: 38338328
Three new molecular complexes (phen)(2-amino-Bz)(H)(BF)·3HO , (phen)(2-amino-5(6)-methyl-Bz)(H)(BF)·HO , and (phen)(1-methyl-2-amino-Bz)(H)(BF) , were prepared by self-assembly of 1,10-phenanthroline (phen) and various substituted 2-aminobenzimidazoles. Confirmation of their structures was established through spectroscopic...
3.
Maurice T, Volle J, Strehaiano M, Crouzier L, Pereira C, Kaloyanov N, et al.
Pharmacol Res . 2019 May; 144:315-330. PMID: 31048034
The sigma-1 (σ) receptor is an endoplasmic reticulum (ER) chaperone protein, enriched in mitochondria-associated membranes. Its activation triggers physiological responses to ER stress and modulate Ca mobilization in mitochondria. Small...
4.
Kaloyanov N, Alexandrova R, Wesselinova D, Mayer-Figge H, Sheldrick W, Dimitrov G
Eur J Med Chem . 2011 Apr; 46(6):1992-6. PMID: 21474217
Novel molecular complexes of 1,10-phenanthroline (phen) and 5-amino-1,10-phenanthroline (5-NH2-phen) [(5-NH2-phen)2(phen) (H2O)3 (1), (phen)2(imidazole) (H+) (BF4-) (2), (phen)2(benzimidazole) (H+) (BF4-) (3), (5-NH2-phen)4(H2O)3 (4), and (phen)3 (indole) (H+) (BF4-) (5)] were synthesized...
5.
Volle J, Filippini D, Krawczy B, Kaloyanov N, van der Lee A, Maurice T, et al.
Org Biomol Chem . 2010 Mar; 8(6):1438-44. PMID: 20204219
In drug discovery, structural modifications over the lead molecule are often crucial for the development of a drug. Herein, we reported the first in vivo bioisosteric effect of phosphinolactone function...
6.
Wesselinova D, Kaloyanov N, Dimitrov G
Eur J Med Chem . 2009 Aug; 44(12):5099-102. PMID: 19683366
The biological activity of previously synthesized compounds [(phen)(3)(H(+))(2)(NO(3)(-))(2) (1), Pd(5-NH(2)-phen)(2)(NO(3))(2) (2) and Pd(phen)(2)(NO(3))(2)(H(2)O) (3)] was investigated in vivo. The three compounds did not show any histological alterations in the observed...
7.
Wesselinova D, Neykov M, Kaloyanov N, Toshkova R, Dimitrov G
Eur J Med Chem . 2009 Mar; 44(6):2720-3. PMID: 19249137
Synthesis and impact on the tumour growth of palladium(II) complex of 5-amino-1,10-phenanthroline Pd(5-NH(2)-phen)(2)(NO(3))(2) and the protonated dimer (phen)(2)(H(+))(BF(4)(-)) have been described. In the reported experiments a cancerous (100% lethality) myeloid...