Nikolai Daraselia
Overview
Explore the profile of Nikolai Daraselia including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
693
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0
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Recent Articles
1.
Cesario A, Auffray C, Agusti A, Apolone G, Balling R, Barbanti P, et al.
Curr Pharm Des
. 2014 Mar;
20(38):5945-56.
PMID: 24641232
Non-Communicable Diseases (NCDs) are among the most pressing global health problems of the twenty-first century. Their rising incidence and prevalence is linked to severe morbidity and mortality, and they are...
2.
Yuryev A, Kotelnikova E, Daraselia N
Expert Opin Drug Discov
. 2013 Mar;
4(12):1307-18.
PMID: 23480468
Importance Of The Field: Drug discovery and development is a very complex and costly process. Understanding the detailed molecular mechanisms of a disease and drug actions can make it more...
3.
Ossovskaya V, Wang Y, Budoff A, Xu Q, Lituev A, Potapova O, et al.
Genes Cancer
. 2012 May;
2(9):870-9.
PMID: 22593799
Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with a high rate of proliferation and metastasis, as well as poor prognosis for advanced-stage disease. Although TNBC was previously...
4.
Kotelnikova E, Shkrob M, Pyatnitskiy M, Ferlini A, Daraselia N
PLoS Comput Biol
. 2012 Feb;
8(2):e1002365.
PMID: 22319435
Elucidation of new biomarkers and potential drug targets from high-throughput profiling data is a challenging task due to a limited number of available biological samples and questionable reproducibility of differential...
5.
Daraselia N, Wang Y, Budoff A, Lituev A, Potapova O, Vansant G, et al.
Am J Cancer Res
. 2011 Dec;
2(1):93-103.
PMID: 22206048
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, with a poor response to chemotherapy and low survival rate. This unfavorable treatment response is likely to...
6.
Kotelnikova E, Yuryev A, Mazo I, Daraselia N
J Bioinform Comput Biol
. 2010 Jun;
8(3):593-606.
PMID: 20556864
Heterogeneous high-throughput biological data become readily available for various diseases. The amount of data points generated by such experiments does not allow manual integration of the information to design the...
7.
Kotelnikova E, Ivanikova N, Kalinin A, Yuryev A, Daraselia N
PLoS One
. 2010 Feb;
5(2):e9256.
PMID: 20174649
Microarray-based expression profiling of living systems is a quick and inexpensive method to obtain insights into the nature of various diseases and phenotypes. A typical microarray profile can yield hundreds...
8.
Sivachenko A, Yuryev A, Daraselia N, Mazo I
J Bioinform Comput Biol
. 2007 Jul;
5(2B):429-56.
PMID: 17636854
Microarray-based characterization of tissues, cellular and disease states, and environmental condition and treatment responses provides genome-wide snapshots containing large amounts of invaluable information. However, the lack of inherent structure within...
9.
Daraselia N, Yuryev A, Egorov S, Mazo I, Ispolatov I
BMC Bioinformatics
. 2007 Jul;
8:243.
PMID: 17620146
Background: Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data mining and processing tools....
10.
Yuryev A, Mulyukov Z, Kotelnikova E, Maslov S, Egorov S, Nikitin A, et al.
BMC Bioinformatics
. 2006 Mar;
7:171.
PMID: 16563163
Background: Scientific literature is a source of the most reliable and comprehensive knowledge about molecular interaction networks. Formalization of this knowledge is necessary for computational analysis and is achieved by...