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Nikola Winter

Explore the profile of Nikola Winter including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 156
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Recent Articles
1.
Rudi O, Hodakova Z, Farias Saad C, Winter N, Grishkovskaya I, Bohm J, et al.
J Mol Biol . 2025 Jan; 437(4):168939. PMID: 39799992
N-degrons are amino-terminal degradation signals. Non-acetylated first residues with bulky side chains were the first discovered N-degrons. In yeast, their ability to destabilize a protein depends on ubiquitin ligase Ubr1,...
2.
Zhang H, Rundle C, Winter N, Miricescu A, Mooney B, Bachmair A, et al.
Plant Cell . 2024 Apr; 36(9):3177-3200. PMID: 38608155
BIG/DARK OVEREXPRESSION OF CAB1/TRANSPORT INHIBITOR RESPONSE3 is a 0.5 MDa protein associated with multiple functions in Arabidopsis (Arabidopsis thaliana) signaling and development. However, the biochemical functions of BIG are unknown....
3.
Bohm J, Winter N, Kozlic A, Telser T, Nehlin L, Bachmair A
Methods Enzymol . 2023 Aug; 686:221-233. PMID: 37532401
Heterologous expression of enzymes can generate a background-free environment that facilitates investigation of enzyme properties, for instance to focus on particular isoforms in case of gene families, or on individual...
4.
Winter N, Marchand R, Lehmann C, Nehlin L, Trapannone R, Rokvic D, et al.
EMBO Rep . 2023 Feb; 24(3):e56683. PMID: 36727294
Addressing climate change and sustainability starts with individuals and moves up to institutional change. Here is what we as scientists in the life sciences can do to enact change.
5.
Talloji P, Nehlin L, Huttel B, Winter N, Cerny M, Dufkova H, et al.
BMC Plant Biol . 2022 Apr; 22(1):183. PMID: 35395773
Background: Many regulatory circuits in plants contain steps of targeted proteolysis, with the ubiquitin proteasome system (UPS) as the mediator of these proteolytic events. In order to decrease ubiquitin-dependent proteolysis,...
6.
Kozlic A, Winter N, Telser T, Reimann J, Rose K, Nehlin L, et al.
Front Plant Sci . 2022 Jan; 12:806129. PMID: 35069663
The N-degron pathway is a branch of the ubiquitin-proteasome system where amino-terminal residues serve as degradation signals. In a synthetic biology approach, we expressed ubiquitin ligase PRT6 and ubiquitin conjugating...
7.
Winter N, Novatchkova M, Bachmair A
Int J Mol Sci . 2021 Apr; 22(7). PMID: 33805528
The first amino acid of a protein has an important influence on its metabolic stability. A number of ubiquitin ligases contain binding domains for different amino-terminal residues of their substrates,...
8.
Winter N, Kragler F
Plant Cell Physiol . 2018 Jul; 59(9):1700-1713. PMID: 30020523
High-throughput studies identified approximately one-fifth of Arabidopsis protein-encoding transcripts to be graft transmissible and to move over long distances in the phloem. In roots, one-fifth of transcription factors were annotated...
9.
Tomanov K, Nukarinen E, Vicente J, Mendiondo G, Winter N, Nehlin L, et al.
J Exp Bot . 2018 May; 69(19):4583-4590. PMID: 29846689
Post-translational modifications are essential mediators between stimuli from development or the environment and adaptive transcriptional patterns. Recent data allow a first glimpse at how two modifications, phosphorylation and sumoylation, act...
10.
Zhang W, Thieme C, Kollwig G, Apelt F, Yang L, Winter N, et al.
Plant Cell . 2016 Jun; 28(6):1237-49. PMID: 27268430
In plants, protein-coding mRNAs can move via the phloem vasculature to distant tissues, where they may act as non-cell-autonomous signals. Emerging work has identified many phloem-mobile mRNAs, but little is...