Nikhil Gaidhani
Overview
Explore the profile of Nikhil Gaidhani including associated specialties, affiliations and a list of published articles.
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5
Citations
32
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Recent Articles
1.
Gaidhani N, Tucci F, Kem W, Beaton G, Uteshev V
Br J Pharmacol
. 2021 Jan;
178(7):1684-1704.
PMID: 33496352
Background And Purpose: Targeting α7 nicotinic ACh receptors (nAChRs) in neuroinflammatory disorders including acute ischaemic stroke holds significant therapeutic promise. However, therapeutically relevant signalling mechanisms remain unidentified. Activation of neuronal...
2.
Gaidhani N, Kem W, Uteshev V
Brain Res
. 2020 Nov;
1751:147196.
PMID: 33159972
Acute ischemic stroke (AIS) causes both central and peripheral inflammation, while activation of α7 nicotinic acetylcholine receptors (nAChRs) provides both central and peripheral anti-inflammatory and anti-apoptotic effects. Here, we provide...
3.
Gaidhani N, Uteshev V
Pharmacol Res
. 2018 Sep;
136:121-132.
PMID: 30205140
To minimize irreversible brain injury after acute ischemic stroke (AIS), the time to treatment (i.e., treatment delay) should be minimized. However, thus far, all cytoprotective clinical trials have failed. Analysis...
4.
Gaidhani N, Sun F, Schreihofer D, Uteshev V
Brain Res Bull
. 2017 Jul;
134:168-176.
PMID: 28755978
Tremendous efforts and funds invested in discovery of novel drug treatments for ischemic stroke have so far failed to deliver clinically efficacious therapies. The reasons for these failures are not...
5.
Uteshev V, Tenovuo O, Gaidhani N
Curr Pharm Des
. 2016 Jan;
22(14):2083-92.
PMID: 26818869
Existing treatments of traumatic brain injury (TBI) have failed to reverse tremendous losses in productivity, independence and overall quality of life among TBI victims and therefore, cannot be viewed as...