Nikhil A Gokhale
Overview
Explore the profile of Nikhil A Gokhale including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
164
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Recent Articles
1.
Gokhale N
Amino Acids
. 2013 Jul;
45(4):751-4.
PMID: 23824360
Proteins with polybasic clusters bind to negatively charged phosphoinositides at the cell membrane. In this review, I have briefly discussed the types of phosphoinositides naturally found on membrane surfaces and...
2.
Gokhale N, Zaremba A, Janoshazi A, Weaver J, Shears S
Biochem J
. 2013 May;
453(3):413-26.
PMID: 23682967
We describe new signalling consequences for PPIP5K1 (diphosphoinositol pentakisphosphate kinase type 1)-mediated phosphorylation of InsP6 and 5-InsP7 to 1-InsP7 and InsP8. In NIH 3T3 cells, either hyperosmotic stress or receptor...
3.
Shears S, Ganapathi S, Gokhale N, Schenk T, Wang H, Weaver J, et al.
Subcell Biochem
. 2012 Mar;
59:389-412.
PMID: 22374098
Ins(1,4,5)P(3) is a classical intracellular messenger: stimulus-dependent changes in its levels elicits biological effects through its release of intracellular Ca(2+) stores. The Ins(1,4,5)P(3) response is "switched off" by its metabolism...
4.
Gokhale N, Zaremba A, Shears S
Biochem J
. 2011 Jan;
434(3):415-26.
PMID: 21222653
The inositol pyrophosphates are multifunctional signalling molecules. One of the families of enzymes that synthesize the inositol pyrophosphates are the Vip1/PPIP5Ks (PP-InsP5 kinases). The kinase domains in Vip1/PPIP5Ks have been...
5.
Shears S, Gokhale N, Wang H, Zaremba A
Adv Enzyme Regul
. 2010 Nov;
51(1):13-25.
PMID: 21035493
In countries where adulthood is considered to be attained at age eighteen, 2011 can be the point at which the diphosphoinositol polyphosphates might formally be described as "coming of age",...
6.
Gokhale N, Abraham A, Digman M, Gratton E, Cho W
J Biol Chem
. 2005 Oct;
280(52):42831-40.
PMID: 16230353
Annexin A2 is a phospholipid-binding protein that forms a heterotetramer (annexin II-p11 heterotetramer; A2t) with p11 (S100A10). It has been reported that annexin A2 is involved in binding to phosphatidylinositol...