Nicole Therville
Overview
Explore the profile of Nicole Therville including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
464
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Recent Articles
11.
Cintas C, Douche T, Therville N, Arcucci S, Ramos-Delgado F, Basset C, et al.
Cancers (Basel)
. 2018 Jun;
10(6).
PMID: 29865155
For patients with metastatic pancreatic cancer that are not eligible for surgery, signal-targeted therapies have so far failed to significantly improve survival. These therapeutic options have been tested in phase...
12.
Morfoisse F, Tatin F, Chaput B, Therville N, Vaysse C, Metivier R, et al.
Arterioscler Thromb Vasc Biol
. 2018 Apr;
38(6):1346-1357.
PMID: 29650694
Objective: Estrogens exert beneficial effect on the blood vascular system. However, their role on the lymphatic system has been poorly investigated. We studied the protective effect of the 17β estradiol-the...
13.
Mrad M, Imbert C, Garcia V, Rambow F, Therville N, Carpentier S, et al.
Oncotarget
. 2016 Oct;
7(44):71873-71886.
PMID: 27708249
The infiltration of melanoma tumors by macrophages is often correlated with poor prognosis. However, the molecular signals that regulate the dialogue between malignant cells and the inflammatory microenvironment remain poorly...
14.
Astudillo L, Therville N, Colacios C, Segui B, Andrieu-Abadie N, Levade T
Biochimie
. 2015 Nov;
125:267-80.
PMID: 26582417
Sphingolipids represent a major class of lipids that are essential constituents of eukaryotic cells. They are predominantly located in plasma membrane microdomains, and play an important structural role in regulating...
15.
Baer R, Cintas C, Therville N, Guillermet-Guibert J
Adv Biol Regul
. 2015 Jul;
59:19-35.
PMID: 26166735
Pancreatic cancer belongs to the incurable family of solid cancers. Despite of a recent better understanding its molecular biology, and an increased number of clinical trials, there is still a...
16.
Loiseau N, Polizzi A, Dupuy A, Therville N, Rakotonirainy M, Loy J, et al.
Arch Toxicol
. 2014 Aug;
89(9):1619-29.
PMID: 25155190
Fumonisin B1 (FB1) is a well-known inhibitor of de novo sphingolipid biosynthesis, due to its ability to inhibit ceramide synthases (CerS) activity. In mammals, this toxin triggers broad clinical symptoms...
17.
Astudillo L, Sabourdy F, Therville N, Bode H, Segui B, Andrieu-Abadie N, et al.
J Inherit Metab Dis
. 2014 Aug;
38(1):65-76.
PMID: 25141825
Monogenic defects of sphingolipid biosynthesis have been recently identified in human patients. These enzyme deficiencies affect the synthesis of sphingolipid precursors, ceramides or complex glycosphingolipids. They are transmitted as autosomal...
18.
Popa I, Therville N, Carpentier S, Levade T, Cuvillier O, Portoukalian J
PLoS One
. 2011 Jun;
6(5):e19974.
PMID: 21629700
Activation of an acid sphingomyelinase (aSMase) leading to a biosynthesis of GD3 disialoganglioside has been associated with Fas-induced apoptosis of lymphoid cells. The present study was undertaken to clarify the...
19.
Veret J, Coant N, Berdyshev E, Skobeleva A, Therville N, Bailbe D, et al.
Biochem J
. 2011 May;
438(1):177-89.
PMID: 21592087
Pancreatic β-cell apoptosis induced by palmitate requires high glucose concentrations. Ceramides have been suggested to be important mediators of glucolipotoxicity-induced β-cell apoptosis. In INS-1 β-cells, 0.4 mM palmitate with 5...
20.
Sabourdy F, Selves J, Astudillo L, Laurent C, Brousset P, Delisle M, et al.
Blood
. 2011 Apr;
117(13):3695-6.
PMID: 21454466
No abstract available.