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Nicole Mastrangelo

Explore the profile of Nicole Mastrangelo including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Chen Y, Kankel M, Hana S, Lau S, Zavodszky M, McKissick O, et al.
Gene Ther . 2022 Nov; 30(5):443-454. PMID: 36450833
CRISPR-based gene editing technology represents a promising approach to deliver therapies for inherited disorders, including amyotrophic lateral sclerosis (ALS). Toxic gain-of-function superoxide dismutase 1 (SOD1) mutations are responsible for ~20%...
2.
Torregrosa T, Lehman S, Hana S, Marsh G, Xu S, Koszka K, et al.
Gene Ther . 2021 Feb; 28(7-8):456-468. PMID: 33612827
Adeno-associated virus (AAV) transduction efficiency and tropism are conventionally determined by high expression of a fluorescent reporter gene. Emerging data has suggested that such conventional methods may underestimate AAV transduction...