Nicole L McIntosh
Overview
Explore the profile of Nicole L McIntosh including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
82
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0
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Recent Articles
1.
McIntosh N, Berguig G, Karim O, Cortesio C, De Angelis R, Khan A, et al.
Sci Rep
. 2022 Nov;
12(1):19754.
PMID: 36396936
No abstract available.
2.
Handyside B, Ismail A, Zhang L, Yates B, Xie L, Sihn C, et al.
Mol Ther
. 2022 Nov;
30(12):3570-3586.
PMID: 36348622
Recombinant adeno-associated virus (rAAV) vectors are often produced in HEK293 or Spodoptera frugiperda (Sf)-based cell lines. We compared expression profiles of "oversized" (∼5,000 bp) and "standard-sized" (4,600 bp) rAAV5-human α1-antitrypsin...
3.
Katsikis G, Hwang I, Wang W, Bhat V, McIntosh N, Karim O, et al.
Nano Lett
. 2022 Feb;
22(4):1511-1517.
PMID: 35148107
Quantifying the composition of viral vectors used in vaccine development and gene therapy is critical for assessing their functionality. Adeno-associated virus (AAV) vectors, which are the most widely used viral...
4.
McIntosh N, Berguig G, Karim O, Cortesio C, De Angelis R, Khan A, et al.
Sci Rep
. 2021 Feb;
11(1):3012.
PMID: 33542328
Adeno associated virus (AAV) capsids are a leading modality for in vivo gene delivery. Complete and precise characterization of capsid particles, including capsid and vector genome concentration, is necessary to...
5.
Johnson T, Morris J, Coppage D, Cook C, Persi L, Ogarrio M, et al.
ACS Med Chem Lett
. 2020 Feb;
11(2):108-113.
PMID: 32071675
Reinvestigation of mycothiazole () revealed picomolar potency (IC = 0.00016, 0.00027, 0.00035 μM) against pancreatic, (PANC-1), liver (HepG2), and colon (HCT-116) tumor cell lines. Reevaluation of provided [α] data indicating...
6.
Johnson T, Milan-Lobo L, Che T, Ferwerda M, Lambu E, McIntosh N, et al.
ACS Chem Neurosci
. 2016 Oct;
8(3):473-485.
PMID: 27744679
Opioid therapeutics are excellent analgesics, whose utility is compromised by dependence. Morphine (1) and its clinically relevant derivatives such as OxyContin (2), Vicodin (3), and Dilaudid (4) are "biased" agonists...