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Nicole Gruenheit

Explore the profile of Nicole Gruenheit including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 370
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Recent Articles
1.
Zwirner S, Abu Rmilah A, Klotz S, Pfaffenroth B, Kloevekorn P, Moschopoulou A, et al.
Cell . 2024 Mar; 187(7):1666-1684.e26. PMID: 38490194
Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver...
2.
Stewart B, Gruenheit N, Baldwin A, Chisholm R, Rozen D, Harwood A, et al.
Nat Commun . 2022 Jan; 13(1):319. PMID: 35031602
Natural selection should favour generalist predators that outperform specialists across all prey types. Two genetic solutions could explain why intraspecific variation in predatory performance is, nonetheless, widespread: mutations beneficial on...
3.
Gruenheit N, Baldwin A, Stewart B, Jaques S, Keller T, Parkinson K, et al.
BMC Biol . 2021 Aug; 19(1):172. PMID: 34429112
Background: Genomes can be sequenced with relative ease, but ascribing gene function remains a major challenge. Genetically tractable model systems are crucial to meet this challenge. One powerful model is...
4.
Luqman A, Zabel S, Rahmdel S, Merz B, Gruenheit N, Harter J, et al.
Front Microbiol . 2020 Dec; 11:573679. PMID: 33335515
Trace amines (TA) are endogenously produced in mammals, have a low concentration in the central nervous system (CNS), but trigger a variety of neurological effects and intervene in host cell...
5.
de Oliveira J, Morales A, Stewart B, Gruenheit N, Engelmoer J, Brown S, et al.
Nat Commun . 2019 Jul; 10(1):3284. PMID: 31337766
Conflict is thought to play a critical role in the evolution of social interactions by promoting diversity or driving accelerated evolution. However, despite our sophisticated understanding of how conflict shapes...
6.
Gruenheit N, Parkinson K, Brimson C, Kuwana S, Johnson E, Nagayama K, et al.
Dev Cell . 2018 Nov; 47(4):494-508.e4. PMID: 30473004
Cell-cell heterogeneity can facilitate lineage choice during embryonic development because it primes cells to respond to differentiation cues. However, remarkably little is known about the origin of heterogeneity or whether...
7.
Voelckel C, Gruenheit N, Lockhart P
Trends Plant Sci . 2017 Apr; 22(6):462-471. PMID: 28365131
Comparative transcriptomics and proteomics (T&P) have brought biological insight into development, gene function, and physiological stress responses. However, RNA-seq and high-throughput proteomics remain underutilised in studies of plant adaptation. These...
8.
Gruenheit N, Parkinson K, Stewart B, Howie J, Wolf J, Thompson C
Nat Commun . 2017 Jan; 8:14171. PMID: 28120827
Cheaters disrupt cooperation by reaping the benefits without paying their fair share of associated costs. Cheater impact can be diminished if cooperators display a tag ('greenbeard') and recognise and preferentially...
9.
Wolf J, Howie J, Parkinson K, Gruenheit N, Melo D, Rozen D, et al.
Curr Biol . 2015 Mar; 25(8):1086-90. PMID: 25819562
Cooperation is ubiquitous across the tree of life, from simple microbes to the complex social systems of animals. Individuals cooperate by engaging in costly behaviors that can be exploited by...
10.
Parkinson K, Baines A, Keller T, Gruenheit N, Bragg L, North R, et al.
Nat Cell Biol . 2013 Dec; 16(1):87-98. PMID: 24335649
Rab GTPases play key roles in the delivery, docking and fusion of intracellular vesicles. However, the mechanism by which spatial and temporal regulation of Rab GTPase activity is controlled is...