Christopher R L Thompson
Overview
Explore the profile of Christopher R L Thompson including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
654
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Recent Articles
1.
Brimson C, Baines R, Sams-Dodd E, Stefanescu I, Evans B, Kuwana S, et al.
Dev Cell
. 2024 Dec;
PMID: 39672161
Oscillatory phenomena play widespread roles in the control of biological systems. In D. discoideum, oscillatory cyclic adenosine monophosphate (cAMP) signaling drives collective behavior and induces a temporal developmental gene expression...
2.
Heslop-Harrison G, Nakabayashi K, Espinosa-Ruiz A, Robertson F, Baines R, Thompson C, et al.
Plant Commun
. 2024 Mar;
5(6):100846.
PMID: 38460510
Allelochemicals represent a class of natural products released by plants as root, leaf, and fruit exudates that interfere with the growth and survival of neighboring plants. Understanding how allelochemicals function...
3.
Belcher L, Madgwick P, Kuwana S, Stewart B, Thompson C, Wolf J
Proc Natl Acad Sci U S A
. 2022 Jul;
119(29):e2111233119.
PMID: 35858311
Organisms often cooperate through the production of freely available public goods. This can greatly benefit the group but is vulnerable to the "tragedy of the commons" if individuals lack the...
4.
Stewart B, Gruenheit N, Baldwin A, Chisholm R, Rozen D, Harwood A, et al.
Nat Commun
. 2022 Jan;
13(1):319.
PMID: 35031602
Natural selection should favour generalist predators that outperform specialists across all prey types. Two genetic solutions could explain why intraspecific variation in predatory performance is, nonetheless, widespread: mutations beneficial on...
5.
Gruenheit N, Baldwin A, Stewart B, Jaques S, Keller T, Parkinson K, et al.
BMC Biol
. 2021 Aug;
19(1):172.
PMID: 34429112
Background: Genomes can be sequenced with relative ease, but ascribing gene function remains a major challenge. Genetically tractable model systems are crucial to meet this challenge. One powerful model is...
6.
Baines R, Wolton K, Thompson C
Toxicol Sci
. 2021 Aug;
183(2):302-318.
PMID: 34387693
A critical aspect of toxicity evaluation is developmental and reproductive toxicity (DART) testing. Traditionally, DART testing has been conducted in vivo in mammalian model systems. New legislation aimed at reducing...
7.
de Oliveira J, Morales A, Hurst L, Urrutia A, Thompson C, Wolf J
Mol Biol Evol
. 2021 Apr;
38(8):3247-3266.
PMID: 33871580
Alternative synonymous codons are often used at unequal frequencies. Classically, studies of such codon usage bias (CUB) attempted to separate the impact of neutral from selective forces by assuming that...
8.
de Oliveira J, Morales A, Stewart B, Gruenheit N, Engelmoer J, Brown S, et al.
Nat Commun
. 2019 Jul;
10(1):3284.
PMID: 31337766
Conflict is thought to play a critical role in the evolution of social interactions by promoting diversity or driving accelerated evolution. However, despite our sophisticated understanding of how conflict shapes...
9.
Aloum L, Brimson C, Zhyvoloup A, Baines R, Bakovic J, Filonenko V, et al.
Biochem Biophys Res Commun
. 2019 Feb;
511(2):294-299.
PMID: 30797553
Dictyostelium discoideum (D. discoideum) is a simple eukaryote with a unique life cycle in which it differentiates from unicellular amoebae into a fruiting body upon starvation. Reactive oxygen species (ROS)...
10.
Gruenheit N, Parkinson K, Brimson C, Kuwana S, Johnson E, Nagayama K, et al.
Dev Cell
. 2018 Nov;
47(4):494-508.e4.
PMID: 30473004
Cell-cell heterogeneity can facilitate lineage choice during embryonic development because it primes cells to respond to differentiation cues. However, remarkably little is known about the origin of heterogeneity or whether...