Nicolas P Andrews
Overview
Explore the profile of Nicolas P Andrews including associated specialties, affiliations and a list of published articles.
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10
Citations
225
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0
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Recent Articles
1.
Duan Z, Andrews N, Chen C, Fan M, Wang J, Shen J, et al.
Oncol Rep
. 2019 Dec;
43(1):318-327.
PMID: 31789405
Bromodomain proteins such as BRD4 chromatin regulator are attractive cancer therapeutic targets. ANCCA (AAA+ nuclear coregulatory cancer‑associated protein, also known as ATPase family AAA domain containing 2 or ATAD2) is...
2.
Andrews N, Boeckman J, Manning C, Nguyen J, Bechtold H, Dumitras C, et al.
Elife
. 2019 Jan;
8.
PMID: 30667360
Generating recombinant monoclonal antibodies (R-mAbs) from mAb-producing hybridomas offers numerous advantages that increase the effectiveness, reproducibility, and transparent reporting of research. We report here the generation of a novel resource...
3.
Turcotte C, Sloat S, Rigothi J, Rosenkranse E, Northrup A, Andrews N, et al.
Genetics
. 2018 Jan;
208(3):991-1007.
PMID: 29339410
Meiotic recombination depends upon the tightly coordinated regulation of chromosome dynamics and is essential for the production of haploid gametes. Central to this process is the formation and repair of...
4.
Turcotte C, Andrews N, Sloat S, Checchi P
Genetics
. 2017 Jan;
204(3):883-891.
PMID: 28114101
The mechanisms cells use to maintain genetic fidelity via DNA repair and the accuracy of these processes have garnered interest from scientists engaged in basic research to clinicians seeking improved...
5.
Kalashnikova E, Revenko A, Gemo A, Andrews N, Tepper C, Zou J, et al.
Cancer Res
. 2010 Sep;
70(22):9402-12.
PMID: 20864510
Chromatin coregulators are important factors in tumorigenesis and cancer progression. ANCCA is an AAA+ ATPase and a bromodomain-containing nuclear coactivator for the estrogen and androgen receptors that is crucial for...
6.
Andrews N, Fujii H, Goronzy J, Weyand C
Gerontology
. 2009 Dec;
56(4):390-403.
PMID: 20016137
A defining feature of the eukaryotic genome is the presence of linear chromosomes. This arrangement, however, poses several challenges with regard to chromosomal replication and maintenance. To prevent the loss...
7.
Andrews N, Pack C, Lukacher A
J Virol
. 2008 Mar;
82(10):4697-705.
PMID: 18337581
The CD8 coreceptor is important for positive selection of major histocompatibility complex I (MHC-I)-restricted thymocytes and in the generation of pathogen-specific T cells. However, the requirement for CD8 in these...
8.
Andrews N, Pack C, Vezys V, Barber G, Lukacher A
J Immunol
. 2007 May;
178(11):7267-75.
PMID: 17513776
Chronic Ag exposure during persistent viral infection erodes virus-specific CD8 T cell numbers and effector function, with a concomitant loss of pathogen control. Less clear are the respective contributions of...
9.
Byers A, Andrews N, Lukacher A
J Immunol
. 2006 May;
176(10):6121-9.
PMID: 16670321
Memory CD8 T cells comprise a critical component of durable immunity because of their capacity to rapidly proliferate and exert effector activity upon Ag rechallenge. During persistent viral infection, memory...
10.
Byers A, Kemball C, Andrews N, Lukacher A
Microbes Infect
. 2003 Mar;
5(2):169-77.
PMID: 12650775
Recent evidence indicates that CD8(+) T cells express natural killer cell receptors that constrain the range and magnitude of their activities. For virus-specific CD8(+) T cells, upregulation of these receptors...