Nicolas Lehrbach
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Explore the profile of Nicolas Lehrbach including associated specialties, affiliations and a list of published articles.
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5
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33
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Recent Articles
1.
Lehrbach N
Trends Biochem Sci
. 2024 Oct;
49(12):1033-1035.
PMID: 39419747
The Nrf1/Nfe2L1 transcription factor is a master regulator of proteasome biogenesis. New work by Yoshida and colleagues reveals a surprising mechanism by which ubiquitination of N-glycosylated Nrf1 controls its function.
2.
Yanagi K, Jochim B, Kunjo S, Breen P, Ruvkun G, Lehrbach N
PLoS Biol
. 2024 Jul;
22(7):e3002720.
PMID: 38991033
The conserved SKN-1A/Nrf1 transcription factor regulates the expression of proteasome subunit genes and is essential for maintenance of adequate proteasome function in animal development, aging, and stress responses. Unusual among...
3.
Yanagi K, Lehrbach N
MicroPubl Biol
. 2024 Jun;
2024.
PMID: 38872845
Transgenic animals are an invaluable tool in model organism genetics. The ease of modifying the genome through high-copy integration of transgenes facilitates the investigation of diverse and fundamental biological processes....
4.
Ruvkun G, Lehrbach N
Cold Spring Harb Perspect Biol
. 2022 Aug;
15(1).
PMID: 35940907
Nrf1 is a member of the nuclear erythroid 2-like family of transcription factors that regulate stress-responsive gene expression in animals. Newly synthesized Nrf1 is targeted to the endoplasmic reticulum (ER)...
5.
Akay A, Craig A, Lehrbach N, Larance M, Pourkarimi E, Wright J, et al.
Open Biol
. 2013 Nov;
3(11):130151.
PMID: 24258276
Messenger RNA translation is regulated by RNA-binding proteins and small non-coding RNAs called microRNAs. Even though we know the majority of RNA-binding proteins and microRNAs that regulate messenger RNA expression,...