Nicolas Lartillot
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Explore the profile of Nicolas Lartillot including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Luiselli J, Rouzaud-Cornabas J, Lartillot N, Beslon G
Genome Biol Evol
. 2024 Nov;
16(12).
PMID: 39566106
Genome streamlining, i.e. genome size reduction, is observed in bacteria with very different life traits, including endosymbiotic bacteria and several marine bacteria, raising the question of its evolutionary origin. None...
2.
Quintero I, Lartillot N, Morlon H
Science
. 2024 May;
384(6699):1007-1012.
PMID: 38815022
The evolutionary histories of major clades, including mammals, often comprise changes in their diversification dynamics, but how these changes occur remains debated. We combined comprehensive phylogenetic and fossil information in...
3.
Genestier A, Duret L, Lartillot N
PLoS Genet
. 2024 May;
20(5):e1011274.
PMID: 38768268
Molecular dissection of meiotic recombination in mammals, combined with population-genetic and comparative studies, have revealed a complex evolutionary dynamic characterized by short-lived recombination hotspots. Hotspots are chromosome positions containing DNA...
4.
Szantho L, Lartillot N, Szollosi G, Schrempf D
Syst Biol
. 2023 Mar;
72(4):767-780.
PMID: 36946562
Accurate phylogenies are fundamental to our understanding of the pattern and process of evolution. Yet, phylogenies at deep evolutionary timescales, with correspondingly long branches, have been fraught with controversy resulting...
5.
Latrille T, Rodrigue N, Lartillot N
Proc Natl Acad Sci U S A
. 2023 Mar;
120(11):e2214977120.
PMID: 36897968
Adaptation in protein-coding sequences can be detected from multiple sequence alignments across species or alternatively by leveraging polymorphism data within a population. Across species, quantification of the adaptive rate relies...
6.
Lartillot N
Syst Biol
. 2023 Feb;
72(3):616-638.
PMID: 36810802
There is still no consensus as to how to select models in Bayesian phylogenetics, and more generally in applied Bayesian statistics. Bayes factors are often presented as the method of...
7.
Latrille T, Lartillot N
Mol Biol Evol
. 2022 Jan;
39(2).
PMID: 35021218
Phylogenetic codon models are routinely used to characterize selective regimes in coding sequences. Their parametric design, however, is still a matter of debate, in particular concerning the question of how...
8.
Charlat S, Ariew A, Bourrat P, Ferreira Ruiz M, Heams T, Huneman P, et al.
Life (Basel)
. 2021 Oct;
11(10).
PMID: 34685422
Natural selection is commonly seen not just as an explanation for adaptive evolution, but as the inevitable consequence of "heritable variation in fitness among individuals". Although it remains embedded in...
9.
Latrille T, Lanore V, Lartillot N
Mol Biol Evol
. 2021 Jun;
38(10):4573-4587.
PMID: 34191010
Mutation-selection phylogenetic codon models are grounded on population genetics first principles and represent a principled approach for investigating the intricate interplay between mutation, selection, and drift. In their current form,...
10.
Brevet M, Lartillot N
Genome Biol Evol
. 2021 Jun;
13(8).
PMID: 34190972
The nearly neutral theory predicts specific relations between effective population size (Ne) and patterns of divergence and polymorphism, which depend on the shape of the distribution of fitness effects (DFE)...