Nicolas Kint
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Explore the profile of Nicolas Kint including associated specialties, affiliations and a list of published articles.
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22
Citations
207
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Recent Articles
1.
Harrison S, Touzeau C, Kint N, Li K, Nguyen T, Mayeur-Rousse C, et al.
N Engl J Med
. 2025 Feb;
392(7):677-685.
PMID: 39938094
We describe two patients in whom malignant monoclonal T-cell lymphoproliferation developed after administration of chimeric antigen receptor (CAR) T-cell therapy with ciltacabtagene autoleucel (cilta-cel) in the phase 3 CARTITUDE-4 trial....
2.
Caulat L, Lotoux A, Martins M, Kint N, Anjou C, Teixeira M, et al.
mBio
. 2024 Aug;
15(10):e0159124.
PMID: 39189748
Importance: The gastrointestinal tract is a hypoxic environment, with the existence of two gradients of O along the gut, one longitudinal anteroposterior decreasing gradient and one proximodistal increasing from the...
3.
Unay J, Kint N, Viollier P
Curr Biol
. 2024 Jun;
34(13):2932-2947.e7.
PMID: 38897200
Many bacteria glycosylate flagellin on serine or threonine residues using pseudaminic acid (Pse) or other sialic acid-like donor sugars. Successful reconstitution of Pse-dependent sialylation by the conserved Maf-type flagellin glycosyltransferase...
4.
Den Berghe T, Verberckmoes B, Kint N, Wallaert S, De Vos N, Algoet C, et al.
Insights Imaging
. 2024 Apr;
15(1):106.
PMID: 38597979
Objectives: Cytogenetic abnormalities are predictors of poor prognosis in multiple myeloma (MM). This paper aims to build and validate a multiparametric conventional and functional whole-body MRI-based prediction model for cytogenetic...
5.
Kint N, Viollier P
Cell Rep
. 2023 Jul;
42(8):112890.
PMID: 37515768
Unidirectional growth of filamentous protein assemblies including the bacterial flagellum relies on dedicated polymerization factors (PFs). The molecular determinants and structural transitions imposed by PFs on multi-subunit assembly are poorly...
6.
Dirven I, Vander Mijnsbrugge A, Mignon S, Tijtgat J, Kint N, Neyns B
Melanoma Res
. 2023 Apr;
33(4):338-344.
PMID: 37114670
Auto-immune hemolytic anemia (AIHA) and hemophagocytic lymphohistiocytosis (HLH) are both rare immune-related adverse events (irAEs) following treatment with immune checkpoint inhibitors. Consensus treatment guidelines are currently lacking. Patients with a...
7.
Kint N, Dubois T, Viollier P
EMBO J
. 2023 Jan;
42(5):e112880.
PMID: 36636824
Glycosylation of surface structures diversifies cells chemically and physically. Nucleotide-activated sialic acids commonly serve as glycosyl donors, particularly pseudaminic acid (Pse) and its stereoisomer legionaminic acid (Leg), which decorate eubacterial...
8.
Delforge M, Raddoux J, Antonis C, Clement C, Kint N, Vanhellemont A, et al.
Onco Targets Ther
. 2022 Mar;
15:243-250.
PMID: 35310960
Purpose: Multiple myeloma (MM) patients with triple- and penta-refractory disease have a poor survival and limited treatment options. Selinexor, in combination with bortezomib and dexamethasone, demonstrated clinical activity in the...
9.
Kint N, Morvan C, Martin-Verstraete I
Curr Opin Microbiol
. 2021 Dec;
65:175-182.
PMID: 34896836
While the gut is typically thought of as anoxic, there are two intersecting and decreasing oxygen gradients that are observed in the gut: oxygen decreases from the small to the...
10.
Kint N, Unay J, Viollier P
Trends Microbiol
. 2021 Nov;
30(2):109-111.
PMID: 34782242
Many bacterial flagella are specifically O-glycosylated with nonulosonic acids, including the sialic acid derivatives, pseudaminic acid or legionaminic acid. Unlike protein glycosyltransferases that are extracytoplasmic, flagellin glycosyltransferases (fGTs) act cytoplasmically...