Nicolas Kint
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Explore the profile of Nicolas Kint including associated specialties, affiliations and a list of published articles.
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22
Citations
207
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Recent Articles
11.
Morvan C, Folgosa F, Kint N, Teixeira M, Martin-Verstraete I
Environ Microbiol
. 2021 Jul;
23(8):4112-4125.
PMID: 34245087
Clostridia comprise bacteria of environmental, biotechnological and medical interest and many commensals of the gut microbiota. Because of their strictly anaerobic lifestyle, oxygen is a major stress for Clostridia. However,...
12.
Delforge M, Vlayen S, Kint N
Expert Rev Hematol
. 2021 Mar;
14(4):365-376.
PMID: 33733978
: Impressive therapeutic progress is being made in the management of multiple myeloma (MM). his progress is related to the introduction of several new classes of therapeutic agents including proteasome...
13.
Ardissone S, Kint N, Petrignani B, Panis G, Viollier P
Dev Cell
. 2020 Oct;
55(4):500-513.e4.
PMID: 33113346
How cellular checkpoints couple the orderly assembly of macromolecular machines with cell-cycle progression is poorly understood. The alpha-proteobacterium Caulobacter crescentus assembles a single polar flagellum during each cell cycle. We...
14.
Kint N, Alves Feliciano C, Martins M, Morvan C, Fernandes S, Folgosa F, et al.
mBio
. 2020 Oct;
11(5).
PMID: 33109769
No abstract available.
15.
Ardissone S, Kint N, Viollier P
Elife
. 2020 Oct;
9.
PMID: 33108275
How specificity is programmed into post-translational modification of proteins by glycosylation is poorly understood, especially for O-linked glycosylation systems. Here we reconstitute and dissect the substrate specificity underpinning the cytoplasmic...
16.
Diallo M, Kint N, Monot M, Collas F, Martin-Verstraete I, van der Oost J, et al.
Front Microbiol
. 2020 Oct;
11:556064.
PMID: 33042064
SpoIIE is a phosphatase involved in the activation of the first sigma factor of the forespore, σ , during sporulation. A Δ mutant of NCIMB 8052, previously generated by CRISPR-Cas9,...
17.
Kint N, Alves Feliciano C, Martins M, Morvan C, Fernandes S, Folgosa F, et al.
mBio
. 2020 Sep;
11(5).
PMID: 32900801
is a major cause of diarrhea associated with antibiotherapy. After germination of spores in the small intestine, vegetative cells are exposed to low oxygen (O) tensions. While considered strictly anaerobic,...
18.
Kint N, Alves Feliciano C, Hamiot A, Denic M, Dupuy B, Martin-Verstraete I
Environ Microbiol
. 2019 Apr;
21(8):2852-2870.
PMID: 31032549
Clostridium difficile is the main cause of antibiotic-associated diarrhoea. Inside the gut, C. difficile must adapt to the stresses it copes with, by inducing protection, detoxification and repair systems that...
19.
Maikova A, Peltier J, Boudry P, Hajnsdorf E, Kint N, Monot M, et al.
Nucleic Acids Res
. 2018 Mar;
46(9):4733-4751.
PMID: 29529286
Clostridium difficile, a major human enteropathogen, must cope with foreign DNA invaders and multiple stress factors inside the host. We have recently provided an experimental evidence of defensive function of...
20.
Neggers J, Kwanten B, Dierckx T, Noguchi H, Voet A, Bral L, et al.
Nat Commun
. 2018 Feb;
9(1):502.
PMID: 29402884
Unraveling the mechanism of action and molecular target of small molecules remains a major challenge in drug discovery. While many cancer drugs target genetic vulnerabilities, loss-of-function screens fail to identify...