Nicolas Jacquelot
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Explore the profile of Nicolas Jacquelot including associated specialties, affiliations and a list of published articles.
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49
Citations
5840
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Recent Articles
1.
Chung D, Shakfa N, Vakharia J, Warner K, Jacquelot N, Sayad A, et al.
Cancer Immunol Res
. 2025 Mar;
:OF1-OF20.
PMID: 40084939
Immunotherapies have had unprecedented success in the treatment of multiple cancer types, albeit with variable response rates. Unraveling the complex network of immune cells within the tumor microenvironment (TME) may...
2.
Chung D, Elford A, Jacquelot N
Methods Cell Biol
. 2025 Jan;
192():1-15.
PMID: 39863384
Breast cancer is the most common cancer in women and continues to have a significant impact in cancer-associated deaths worldwide. Investigating the complex roles of infiltrating immune subsets within the...
3.
Lamorte S, Elford A, Chung D, Murakami K, McGaha T, Jacquelot N
Methods Cell Biol
. 2024 Jun;
188:153-169.
PMID: 38880522
Pancreatic cancer remains an unmet medical need. Late diagnosis and the lack of efficient treatment significantly impact the prognosis of patients suffering from pancreatic cancer. Improving patient outcomes requires a...
4.
Huang Q, H J Cao W, Curio S, Yu H, Denman R, Chen E, et al.
Sci Immunol
. 2024 May;
9(95):eadj2654.
PMID: 38820141
Tissue-resident innate lymphoid cells (ILCs) play a vital role in the frontline defense of various tissues, including the lung. The development of type 2 ILCs (ILC2s) depends on transcription factors...
5.
Characterization of innate lymphoid cell subsets infiltrating melanoma and epithelial ovarian tumors
Chung D, Ghaedi M, Warner K, Sayad A, Saibil S, Bernardini M, et al.
Oncoimmunology
. 2024 May;
13(1):2349347.
PMID: 38746870
The innate lymphoid cell (ILC) family is composed of heterogeneous innate effector and helper immune cells that preferentially reside in tissues where they promote tissue homeostasis. In cancer, they have...
6.
Jacquelot N, Xiong L, H J Cao W, Huang Q, Yu H, Sayad A, et al.
Mucosal Immunol
. 2024 Mar;
17(3):371-386.
PMID: 38492744
Interleukin-(IL) 22 production by intestinal group 3 innate lymphoid cells (ILC3) is critical to maintain gut homeostasis. However, IL-22 needs to be tightly controlled; reduced IL-22 expression is associated with...
7.
Seo H, Verma A, Kinzel M, Huang Q, Mahoney D, Jacquelot N
Pharmaceutics
. 2023 Jul;
15(7).
PMID: 37514187
Reinvigorating the killing function of tumor-infiltrating immune cells through the targeting of regulatory molecules expressed on lymphocytes has markedly improved the prognosis of cancer patients, particularly in melanoma. While initially...
8.
Patton T, Zhao Z, Lim X, Eddy E, Wang H, Nelson A, et al.
Cell Death Dis
. 2023 Feb;
14(2):111.
PMID: 36774342
Cell death mechanisms in T lymphocytes vary according to their developmental stage, cell subset and activation status. The cell death control mechanisms of mucosal-associated invariant T (MAIT) cells, a specialized...
9.
Yu H, Jacquelot N, Belz G
J Exp Med
. 2022 Oct;
219(11).
PMID: 36301303
Innate and adaptive immune cells are found in distinct tissue niches where they orchestrate immune responses. This requires intrinsic and temporal metabolic adaptability to coordinately activate the immune response cascade....
10.
Warner K, Ghaedi M, Chung D, Jacquelot N, Ohashi P
Front Immunol
. 2022 Aug;
13:948358.
PMID: 36032129
Innate and adaptive immune cells monitor, recognize, and eliminate transformed cells. Innate lymphoid cells (ILCs) are innate counterparts of T cells that play a key role in many facets of...