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Nicolas J-F Dreyfus

Explore the profile of Nicolas J-F Dreyfus including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Kielbasa W, Goldsmith P, Donnelly K, Nuthall H, Shcherbinin S, Fleisher A, et al.
Alzheimers Dement (N Y) . 2025 Jan; 10(4):e70020. PMID: 39748851
Introduction: The aggregation and spread of hyperphosphorylated, pathological tau in the human brain is hypothesized to play a key role in Alzheimer's disease (AD) as well as other neurogenerative tauopathies....
2.
Lu S, Haskali M, Ruley K, Dreyfus N, DuBois S, Paul S, et al.
Sci Transl Med . 2020 May; 12(543). PMID: 32404505
We aimed to develop effective radioligands for quantifying brain -linked-β--acetyl-glucosamine (-GlcNAc) hydrolase (OGA) using positron emission tomography in living subjects as tools for evaluating drug target engagement. Posttranslational modifications of...