Nicolas Hohmann
Overview
Explore the profile of Nicolas Hohmann including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
35
Citations
554
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dose-dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin
Hohmann N, Friedrichs A, Burhenne J, Blank A, Mikus G, Haefeli W
Clin Transl Sci
. 2024 Aug;
17(8):e70007.
PMID: 39152679
The dose dependence of the effect of enzyme inducers and the effect of the combined administration of two inducers that exert their effect via the same induction pathway (pregnane X...
2.
Hohmann N, Sprick M, Pohl M, Ahmed A, Burhenne J, Kirchner M, et al.
Clin Transl Sci
. 2023 Nov;
16(12):2483-2493.
PMID: 37920921
Expression of CYP3A5 protein is a basal and acquired resistance mechanism of pancreatic ductal adenocarcinoma cells conferring protection against the CYP3A and CYP2C8 substrate paclitaxel through metabolic degradation. Inhibition of...
3.
Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC
Zhou X, An J, Kurilov R, Brors B, Hu K, Peccerella T, et al.
Nat Cancer
. 2023 Sep;
4(9):1362-1381.
PMID: 37679568
Neoadjuvant chemotherapy can improve the survival of individuals with borderline and unresectable pancreatic ductal adenocarcinoma; however, heterogeneous responses to chemotherapy remain a significant clinical challenge. Here, we performed RNA sequencing...
4.
Hohmann N, Schroder F, Moreira B, Teng H, Burhenne J, Bruckner T, et al.
Alcohol Alcohol
. 2022 Dec;
58(2):134-141.
PMID: 36562601
Aims: Alcohol-associated liver disease (ALD) is a global health problem caused, among other factors, by oxidative stress from the formation of reactive oxygen species (ROS). One important source of ROS...
5.
Nassar Y, Hohmann N, Michelet R, Gottwalt K, Meid A, Burhenne J, et al.
Clin Pharmacokinet
. 2022 Oct;
61(11):1595-1607.
PMID: 36195807
Background: Cytochrome P450 (CYP) 3A contributes to the metabolism of many approved drugs. CYP3A perpetrator drugs can profoundly alter the exposure of CYP3A substrates. However, effects of such drug-drug interactions...
6.
Blank A, Hohmann N, Dettmer M, Manka-Stuhlik A, Mikus G, Stoll F, et al.
Clin Transl Sci
. 2022 Jul;
15(10):2366-2377.
PMID: 35869929
HDIT101 is a first-in-class humanized monoclonal antibody recognizing a conserved epitope in glycoprotein B, a target present on the surface of herpes simplex virus 1 (HSV-1) and HSV-2 particles as...
7.
Neuman M, Seitz H, Teschke R, Malnick S, Johnson-Davis K, Cohen L, et al.
Curr Issues Mol Biol
. 2022 Jun;
44(3):1294-1315.
PMID: 35723310
Hepatic cells are sensitive to internal and external signals. Ethanol is one of the oldest and most widely used drugs in the world. The focus on the mechanistic engine of...
8.
Suarez-Carmona M, Williams A, Schreiber J, Hohmann N, Pruefer U, Krauss J, et al.
J Immunother Cancer
. 2021 Oct;
9(10).
PMID: 34607895
Background: Immunotherapy in microsatellite stable colorectal or pancreatic cancer has not shown promising results. It has been hypothesized that targeting immunosuppressive molecules like SDF1-alpha/CXCL12 could contribute to immunotherapy and animal...
9.
Hajda J, Leuchs B, Angelova A, Frehtman V, Rommelaere J, Mertens M, et al.
Clin Cancer Res
. 2021 Aug;
27(20):5546-5556.
PMID: 34426438
Purpose: To investigate the safety, clinical efficacy, virus pharmacokinetics, shedding, and immune response after administration of an oncolytic parvovirus (H-1PV, ParvOryx) to patients with metastatic pancreatic ductal adenocarcinoma (PDAC) refractory...
10.
Hohmann N, Schroder F, Moreira B, Teng H, Burhenne J, Bruckner T, et al.
Gut
. 2021 May;
71(4):842-844.
PMID: 33972357
No abstract available.