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Nicolas G Bazan

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Articles 246
Citations 13464
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Recent Articles
1.
Bazan N, Obenaus A, Khoutorova L, Mukherjee P, Jun B, Semikov R, et al.
Biomedicines . 2024 Nov; 12(11). PMID: 39595120
Background: In the United States, traumatic brain injury (TBI) contributes significantly to mortality and morbidity. Elovanoids (ELVs), a novel class of homeostatic lipid mediators we recently discovered and characterized, have...
2.
Walkowski W, Richards-Zawacki C, Gordon W, Bazan N, Farris H
PLoS One . 2024 Nov; 19(11):e0312578. PMID: 39541311
Research on visually driven behavior in anurans has often focused on Dendrobatoidea, a clade with extensive variation in skin reflectance, which is perceived to range from cryptic to conspicuous coloration....
3.
Do Carmo S, Kautzmann M, Bhattacharjee S, Jun B, Steinberg C, Emmerson J, et al.
J Neuroinflammation . 2024 Jul; 21(1):185. PMID: 39080670
Background: Brain inflammation contributes significantly to the pathophysiology of Alzheimer's disease, and it is manifested by glial cell activation, increased production of cytokines/chemokines, and a shift in lipid mediators from...
4.
Wang Y, Zhang X, Biverstal H, Bazan N, Tan S, Li N, et al.
Neural Regen Res . 2024 Jun; 20(3):873-886. PMID: 38886959
JOURNAL/nrgr/04.03/01300535-202503000-00031/figure1/v/2024-06-17T092413Z/r/image-tiff Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the...
5.
Bazan H, Bhattacharjee S, Reid M, Jun B, Polk C, Strain M, et al.
Sci Rep . 2024 May; 14(1):11103. PMID: 38750093
Safe and effective pain management is a critical healthcare and societal need. The potential for acute liver injury from paracetamol (ApAP) overdose; nephrotoxicity and gastrointestinal damage from chronic non-steroidal anti-inflammatory...
6.
Runde B, Alapati A, Bazan N
Brain Sci . 2024 Mar; 14(3). PMID: 38539600
The development of noninvasive and cost-effective methods of detecting Alzheimer's disease (AD) is essential for its early prevention and mitigation. We optimize the detection of AD using natural language processing...
7.
Lu Y, Tian H, Peng H, Wang Q, Bunnell B, Bazan N, et al.
Front Cell Dev Biol . 2024 Mar; 12:1380059. PMID: 38533089
Stem cells can be used to treat diabetic mellitus and complications. ω3-docosahexaenoic acid (DHA) derived lipid mediators are inflammation-resolving and protective. This study found novel DHA-derived 7,14-dihydroxy-4,8,10,12,16,19-docosahexaenoic acid (7,14-diHDHA), a...
8.
Runde B, Alapati A, Bazan N
medRxiv . 2024 Jan; PMID: 38293012
As the impact of Alzheimer's disease (AD) is projected to grow in the coming decades as the world's population ages, the development of noninvasive and cost-effective methods of detecting AD...
9.
Calandria J, Bhattacharjee S, Kala-Bhattacharjee S, Mukherjee P, Feng Y, Vowinckel J, et al.
Cell Death Dis . 2023 Dec; 14(12):819. PMID: 38086796
The thioredoxin (TXN) system is an NADPH + H/FAD redox-triggered effector that sustains homeostasis, bioenergetics, detoxifying drug networks, and cell survival in oxidative stress-related diseases. Elovanoid (ELV)-N34 is an endogenously...
10.
Swinkels D, Kocherlakota S, Das Y, Dane A, Wever E, Vaz F, et al.
Invest Ophthalmol Vis Sci . 2023 Nov; 64(14):10. PMID: 37934161
Purpose: Patients deficient in peroxisomal β-oxidation, which is essential for the synthesis of docosahexaenoic acid (DHA, C22:6n-3) and breakdown of very-long-chain polyunsaturated fatty acids (VLC-PUFAs), both important components of photoreceptor...