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Nicolas Chartrel

Explore the profile of Nicolas Chartrel including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 671
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Recent Articles
1.
Devere M, Takhlidjt S, Godefroy D, do Rego J, do Rego J, Do Rego J, et al.
J Endocrinol . 2025 Mar; PMID: 40066929
The present study aims to investigate the impact of orexin deficiency on the regulation of energy and glucose metabolism using a mouse model depleted for the prepro-orexin gene. Our data...
2.
Khiar H, Leveque E, Lopez A, Moreau-Grange L, Richard L, Brunel V, et al.
Diabetes Obes Metab . 2024 Oct; 26(12):5556-5568. PMID: 39350486
Aim: To investigate the evolution of the incretin-like peptide 26RFa in a prospective cohort of women living with obesity with or without type 2 diabetes (T2D) before and after sleeve...
3.
Seitz J, Lahaye E, Andreani N, Thomas B, Takhlidjt S, Chartrel N, et al.
Neuroendocrinology . 2024 Jun; 114(10):907-920. PMID: 38852579
Introduction: Immunoglobulins (Ig) reactive with α-melanocyte-stimulating hormone (α-MSH), an anorexigenic neuropeptide, are present in humans and were previously associated with eating disorders. In this longitudinal study involving patients with anorexia...
4.
Devere M, Takhlidjt S, Prevost G, Chartrel N, Leprince J, Picot M
Neuroendocrinology . 2024 Apr; 115(2):111-127. PMID: 38599200
Background: Obesity and type 2 diabetes are strongly associated pathologies, currently considered as a worldwide epidemic problem. Understanding the mechanisms that drive the development of these diseases would enable to...
5.
Vaeroy H, Lahaye E, Dubessy C, Benard M, Nicol M, Cherifi Y, et al.
Discov Ment Health . 2023 Nov; 3(1):21. PMID: 37983005
Oxytocin is a neuropeptide produced mainly in the hypothalamus and secreted in the CNS and blood. In the brain, it plays a major role in promoting social interactions. Here we...
6.
Zolotarev V, Murovets V, Sepp A, Sozontov E, Lukina E, Khropycheva R, et al.
Int J Mol Sci . 2023 Jul; 24(13). PMID: 37445766
A commercial strain of () 4597 bacteria was shown to reduce food intake and promote weight loss, effects possibly induced by the bacterial protein ClpB, an antigen-mimetic of the anorexigenic...
7.
Seifinejad A, Ramosaj M, Shan L, Li S, Possovre M, Pfister C, et al.
Proc Natl Acad Sci U S A . 2023 May; 120(19):e2220911120. PMID: 37126681
Narcolepsy with cataplexy is a sleep disorder caused by deficiency in the hypothalamic neuropeptide hypocretin/orexin (HCRT), unanimously believed to result from autoimmune destruction of hypocretin-producing neurons. HCRT deficiency can also...
8.
Morel C, Martinez Sanchez I, Cherifi Y, Chartrel N, Diaz Heijtz R
Neuropharmacology . 2023 Mar; 229:109479. PMID: 36870672
The gut microbiota is increasingly recognized as a key environmental factor that shapes host development and physiology, including neural circuits formation and function. Concurrently, there has been growing concern that...
9.
Vaeroy H, Takhlidjt S, Cherifi Y, Lahaye E, Chartrel N, Fetissov S
Brain Sci . 2023 Feb; 13(2). PMID: 36831780
26RFa, also referred to as QRFP, is a hypothalamic neuropeptide mainly known for its role in the regulation of appetite and glucose metabolism. Its possible relevance to emotional regulation is...
10.
Le Solliec M, Arabo A, Takhlidjt S, Maucotel J, Devere M, Berrahmoune H, et al.
Neuropeptides . 2023 Feb; 98:102326. PMID: 36791581
The regulatory peptide 26RFa (QRFP) is involved in the control of glucose homeostasis at the periphery by acting as an incretin, and in the brain by mediating the central antihyperglycemic...