Nico Ortlieb
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Explore the profile of Nico Ortlieb including associated specialties, affiliations and a list of published articles.
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6
Citations
21
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Recent Articles
1.
Ortlieb N, Klenk E, Kulik A, Niedermeyer T
PLoS One
. 2021 Nov;
16(11):e0258934.
PMID: 34739482
Natural products are an important source of lead compounds for the development of drug substances. Actinomycetes have been valuable especially for the discovery of antibiotics. Increasing occurrence of antibiotic resistance...
2.
Wex K, Saur J, Handel F, Ortlieb N, Mokeev V, Kulik A, et al.
Cell Chem Biol
. 2021 Mar;
28(8):1242-1252.e4.
PMID: 33761329
A big challenge in natural product research of today is rapid dereplication of already known substances, to free capacities for the exploration of new agents. Prompt information on bioactivities and...
3.
Kirchner N, Cano-Prieto C, Schulz-Fincke A, Gutschow M, Ortlieb N, Moschny J, et al.
J Nat Prod
. 2020 Dec;
84(1):101-109.
PMID: 33382250
Genome mining of the bacterial strains sp. SH-C52 and DSM 11579 showed that both strains contained a highly similar gene cluster encoding an octamodular nonribosomal peptide synthetase (NRPS) system which...
4.
Buchmann A, Cano-Prieto C, Nafis A, Barakate M, Baz M, Hassani L, et al.
Microbiol Resour Announc
. 2019 Jan;
8(1).
PMID: 30637404
Streptomyces sp. strain Z26 exhibited antifungal activity and turned out to be a producer of the secondary metabolites novonestmycin A and B. The 6.5-Mb draft genome gives insight into the...
5.
Ortlieb N, Keilhofer N, Schrey S, Gross H, Niedermeyer T
Microbiol Resour Announc
. 2018 Dec;
7(14).
PMID: 30533708
sp. strain AcE210 exhibited antibacterial activity toward Gram-positive microorganisms and turned out to be a rare producer of the specialized metabolite xanthocidin. The 10.6-Mb draft genome sequence gives insight into...
6.
Ortlieb N, Bretzel K, Kulik A, Haas J, Ludeke S, Keilhofer N, et al.
Chembiochem
. 2018 Oct;
19(23):2472-2480.
PMID: 30300957
Xanthocidin and six new derivatives were isolated from the endophytic Streptomyces sp. AcE210. Their planar structures were elucidated by 1D and 2D NMR spectroscopy as well as by HRMS. The...