Nicklaus A Sparrow
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Explore the profile of Nicklaus A Sparrow including associated specialties, affiliations and a list of published articles.
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10
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175
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Recent Articles
1.
Sparrow N, Guidry G, Anwar F, Darwish S, Kelly S, Karumanchi S, et al.
Front Med (Lausanne)
. 2022 Nov;
9:987202.
PMID: 36405620
Prone positioning is an established treatment for severe acute lung injury conditions. Neuronal dysfunction frequently occurs with mechanical ventilation-induced acute lung injury (VILI) and clinically manifests as delirium. We previously...
2.
Guidry G, Sparrow N, Marshall H, de Souza Santos R, Bharath S, Gezalian M, et al.
Sci Rep
. 2022 Nov;
12(1):19622.
PMID: 36380004
Urinary tract infections (UTIs) are common and frequently precipitate delirium-like states. Advanced age coincident with the postmenopausal period is a risk factor for delirium following UTIs. We previously demonstrated a...
3.
Anwar F, Sparrow N, Rashid M, Guidry G, Gezalian M, Ley E, et al.
Crit Care
. 2022 Sep;
26(1):274.
PMID: 36100846
Acute neuropsychiatric impairments occur in over 70% of patients with acute lung injury. Mechanical ventilation is a well-known precipitant of acute lung injury and is strongly associated with the development...
4.
Rashid M, Sparrow N, Anwar F, Guidry G, Covarrubias A, Pang H, et al.
J Neuroinflammation
. 2021 Oct;
18(1):247.
PMID: 34711238
Background: Urinary tract infection (UTI) is frequently implicated as a precipitant of delirium, which refers to an acute confusional state that is associated with high mortality, increased length of stay,...
5.
Sparrow N, Anwar F, Covarrubias A, Rajput P, Rashid M, Nisson P, et al.
Am J Respir Cell Mol Biol
. 2021 May;
65(4):403-412.
PMID: 34014798
Mechanical ventilation is a known risk factor for delirium, a cognitive impairment characterized by dysfunction of the frontal cortex and hippocampus. Although IL-6 is upregulated in mechanical ventilation-induced lung injury...
6.
Pestoni J, Klingeman Plati S, Valdivia Camacho O, Fuse M, Onatunde M, Sparrow N, et al.
J Biol Chem
. 2019 Jun;
294(30):11354-11368.
PMID: 31171721
Neurofibromatosis type 2 (NF2) is an autosomal-dominant disorder characterized by the development of bilateral vestibular schwannomas. The gene encodes the tumor suppressor merlin, and loss of merlin activity promotes tumorigenesis...
7.
Petrilli A, Fuse M, Donnan M, Bott M, Sparrow N, Tondera D, et al.
Am J Transl Res
. 2014 Nov;
6(5):471-93.
PMID: 25360213
Mutations in the merlin tumor suppressor gene cause Neurofibromatosis type 2 (NF2), which is a disease characterized by development of multiple benign tumors in the nervous system. The current standard...
8.
Franco M, Ye Y, Refakis C, Feldman J, Stokes A, Basso M, et al.
Proc Natl Acad Sci U S A
. 2013 Mar;
110(12):E1102-11.
PMID: 23487751
Oxidative stress is a widely recognized cause of cell death associated with neurodegeneration, inflammation, and aging. Tyrosine nitration in these conditions has been reported extensively, but whether tyrosine nitration is...
9.
Douglass K, Sparrow N, Bott M, Fernandez-Valle C, Dogariu A
J Biophotonics
. 2012 Aug;
6(5):387-92.
PMID: 22887747
Schwann cell motility was observed on laminin-coated quartz cylinders with different curvatures over an 18 hour period. A new analysis based on difference images helped to determine the minimal radius...
10.
Thaxton C, Bott M, Walker B, Sparrow N, Lambert S, Fernandez-Valle C
Mol Cell Neurosci
. 2010 Dec;
47(1):1-9.
PMID: 21182951
The Neurofibromatosis type 2 tumor suppressor, schwannomin (Sch) is a plasma membrane-cytoskeleton linking protein that regulates receptor signaling and actin dynamics. We examined Sch's role in specifying morphological changes needed...