Nick A van Huizen
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Explore the profile of Nick A van Huizen including associated specialties, affiliations and a list of published articles.
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16
Citations
198
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Recent Articles
1.
Verstegen M, Roos F, Burka K, Gehart H, Jager M, de Wolf M, et al.
Sci Rep
. 2020 Dec;
10(1):21900.
PMID: 33318612
The development, homeostasis, and repair of intrahepatic and extrahepatic bile ducts are thought to involve distinct mechanisms including proliferation and maturation of cholangiocyte and progenitor cells. This study aimed to...
2.
van Huizen N, Burgers P, van Rosmalen J, Doukas M, IJzermans J, Luider T
Front Oncol
. 2020 Oct;
10:557737.
PMID: 33117689
Collagen is significantly upregulated in colorectal liver metastasis (CRLM) compared to liver tissue. Expression levels of specific collagen types in CRLM resemble those in colorectal cancer (CRC) and colon tissue....
3.
van Huizen N, van Rosmalen J, Dekker L, Coebergh van den Braak R, Verhoef C, IJzermans J, et al.
J Proteome Res
. 2019 Nov;
19(1):153-160.
PMID: 31721589
Previously, we reported a combination of an urine collagen alpha-1(I) natural occurring peptide (NOP) AGPP(-OH)GEAGKP(-OH)GEQGVP(-OH)GDLGAP(-OH)GP (AGP) and serum carcinoembryonic antigen (CEA) to have the potential to detect colorectal liver metastasis...
4.
van Huizen N, Holmes J, Burgers P
J Mass Spectrom
. 2019 Nov;
55(7):e4462.
PMID: 31697855
From the NIST website and the literature, we have collected the Ionisation Energies (IE) of 3,052 and the Proton Affinities (PA) of 1,670 compounds. For 614 of these, both the...
5.
van Huizen N, IJzermans J, Burgers P, Luider T
Mass Spectrom Rev
. 2019 Sep;
39(4):309-335.
PMID: 31498911
Mass spectrometry-based techniques can be applied to investigate collagen with respect to identification, quantification, supramolecular organization, and various post-translational modifications. The continuous interest in collagen research has led to a...
6.
van Huizen N, Burgers P, Saintmont F, Brocorens P, Gerbaux P, Stingl C, et al.
J Proteome Res
. 2019 Apr;
18(5):2045-2051.
PMID: 30945869
Collagen has a triple helix form, structured by a [-Gly-Xaa-Yaa-] repetition, where Xaa and Yaa are amino acids. This repeating unit can be post-translationally modified by enzymes, where proline is...
7.
van Huizen N, Coebergh van den Braak R, Doukas M, Dekker L, IJzermans J, Luider T
J Biol Chem
. 2018 Nov;
294(1):281-289.
PMID: 30409905
Changes to extracellular matrix (ECM) structures are linked to tumor cell proliferation and metastasis. We previously reported that naturally occurring peptides of collagen type I are elevated in urine of...
8.
Holmes J, van Huizen N, Burgers P
Eur J Mass Spectrom (Chichester)
. 2017 Nov;
23(6):341-350.
PMID: 29183197
Proton affinities of a number of alkyl acetates (CH-C(=O)-OR) and of methyl alkanoates (R-C(=O)-OCH, R=H, alkyl) have been assembled from the literature or measured using the kinetic method. It was...
9.
Verstegen M, Willemse J, van den Hoek S, Kremers G, Luider T, van Huizen N, et al.
Stem Cells Dev
. 2017 Jul;
26(18):1304-1315.
PMID: 28665233
Liver transplantation is the only effective treatment for end-stage liver disease, but absolute donor shortage remains a limiting factor. Recent advances in tissue engineering focus on generation of native extracellular...
10.
van Huizen N, Luider T, Jobst K, Terlouw J, Holmes J, Burgers P
Eur J Mass Spectrom (Chichester)
. 2016 Jul;
22(2):61-70.
PMID: 27419899
Relative affinity measurements of monovalent metal ions (= Li(+), Cu(+) and Ag(+)) towards aliphatic amines, alcohols and methyl alkanoates (P) have been performed using the kinetic method on the dissociation...