Nicholas W Griffin
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Explore the profile of Nicholas W Griffin including associated specialties, affiliations and a list of published articles.
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16
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4030
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Recent Articles
1.
Iqbal N, Chen R, Griffin N, Hibberd M, Khalid A, Sadiq K, et al.
mSphere
. 2024 May;
9(6):e0019624.
PMID: 38742887
Environmental enteric dysfunction (EED) is a subclinical syndrome of altered small intestinal function postulated to be an important contributor to childhood undernutrition. The role of small intestinal bacterial communities in...
2.
Luccia B, Ahern P, Griffin N, Cheng J, Guruge J, Byrne A, et al.
Cell Host Microbe
. 2020 Apr;
27(6):899-908.e5.
PMID: 32348782
Undernourished children in low-income countries often exhibit poor responses to oral vaccination. Perturbed microbiota development is linked to undernutrition, but whether and how microbiota changes affect vaccine responsiveness remains unclear....
3.
Feng L, Raman A, Hibberd M, Cheng J, Griffin N, Peng Y, et al.
Proc Natl Acad Sci U S A
. 2020 Jan;
117(5):2622-2633.
PMID: 31969452
Human gut microbiota development has been associated with healthy growth but understanding the determinants of community assembly and composition is a formidable challenge. We cultured bacteria from serially collected fecal...
4.
Rouhani S, Griffin N, Penataro Yori P, Gehrig J, Paredes Olortegui M, Siguas Salas M, et al.
Clin Infect Dis
. 2019 Nov;
71(4):989-999.
PMID: 31773127
Background: Detrimental effects of diarrhea on child growth and survival are well documented, but details of the underlying mechanisms remain poorly understood. Recent evidence demonstrates that perturbations to normal development...
5.
Rouhani S, Griffin N, Penataro Yori P, Paredes Olortegui M, Siguas Salas M, Rengifo Trigoso D, et al.
Clin Infect Dis
. 2019 Nov;
71(4):1000-1007.
PMID: 31773126
Background: Campylobacter infection is associated with impaired growth of children, even in the absence of symptoms. To examine the underlying mechanisms, we evaluated associations between Campylobacter infection, linear growth, and...
6.
Ma H, Sales V, Wolf A, Subramanian S, Matthews T, Chen M, et al.
Endocrinology
. 2017 Jun;
158(8):2441-2452.
PMID: 28637315
Prenatal undernutrition and low birth weight are associated with risk of type 2 diabetes and obesity. Prenatal caloric restriction results in low birth weight, glucose intolerance, obesity, and reduced plasma...
7.
Hibberd M, Wu M, Rodionov D, Li X, Cheng J, Griffin N, et al.
Sci Transl Med
. 2017 May;
9(390).
PMID: 28515336
Vitamin and mineral (micronutrient) deficiencies afflict 2 billion people. Although the impact of these imbalances on host biology has been studied extensively, much less is known about their effects on...
8.
Griffin N, Ahern P, Cheng J, Heath A, Ilkayeva O, Newgard C, et al.
Cell Host Microbe
. 2017 Jan;
21(1):84-96.
PMID: 28041931
Ensuring that gut microbiota respond consistently to prescribed dietary interventions, irrespective of prior dietary practices (DPs), is critical for effective nutritional therapy. To address this, we identified DP-associated gut bacterial...
9.
Semenkovich N, Planer J, Ahern P, Griffin N, Lin C, Gordon J
Proc Natl Acad Sci U S A
. 2016 Dec;
113(51):14805-14810.
PMID: 27911843
The gut microbiota impacts many aspects of host biology including immune function. One hypothesis is that microbial communities induce epigenetic changes with accompanying alterations in chromatin accessibility, providing a mechanism...
10.
Wu M, McNulty N, Rodionov D, Khoroshkin M, Griffin N, Cheng J, et al.
Science
. 2015 Oct;
350(6256):aac5992.
PMID: 26430127
Libraries of tens of thousands of transposon mutants generated from each of four human gut Bacteroides strains, two representing the same species, were introduced simultaneously into gnotobiotic mice together with...