Nicholas Van Sciver
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Explore the profile of Nicholas Van Sciver including associated specialties, affiliations and a list of published articles.
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10
Citations
101
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Recent Articles
1.
Li S, Wang M, Van Sciver N, Szymula A, Tumuluri V, George A, et al.
PLoS Pathog
. 2024 Jan;
20(1):e1011907.
PMID: 38232124
Kaposi's sarcoma herpesvirus (KSHV) is a leading cause of malignancy in AIDS and current therapies are limited. Like all herpesviruses, KSHV infection can be latent or lytic. KSHV latency-associated nuclear...
2.
Li S, Liu B, Tan M, Juillard F, Szymula A, Alvarez A, et al.
Nucleic Acids Res
. 2024 Jan;
52(4):1814-1829.
PMID: 38180827
To establish lifelong, latent infection, herpesviruses circularize their linear, double-stranded, DNA genomes through an unknown mechanism. Kaposi's sarcoma (KS) herpesvirus (KSHV), a gamma herpesvirus, is tightly linked with KS, primary...
3.
Szymula A, Samayoa-Reyes G, Ogolla S, Liu B, Li S, George A, et al.
Cell Rep
. 2023 Jul;
42(7):112767.
PMID: 37440412
Kaposi's sarcoma herpesvirus (KSHV) establishes lifelong infection and persists in latently infected B cells. Paradoxically, in vitro B cell infection is inefficient, and cells rapidly die, suggesting the absence of...
4.
Van Sciver N, Ohashi M, Nawandar D, Pauly N, Lee D, Makielski K, et al.
PLoS Pathog
. 2021 Nov;
17(11):e1010045.
PMID: 34748616
Epstein-Barr virus (EBV) is a human herpesvirus that causes infectious mononucleosis and contributes to both B-cell and epithelial-cell malignancies. EBV-infected epithelial cell tumors, including nasopharyngeal carcinoma (NPC), are largely composed...
5.
Van Sciver N, Ohashi M, Pauly N, Bristol J, Nelson S, Johannsen E, et al.
PLoS Pathog
. 2021 Aug;
17(8):e1009783.
PMID: 34339458
The Epstein-Barr virus (EBV) human herpesvirus is associated with B-cell and epithelial-cell malignancies, and both the latent and lytic forms of viral infection contribute to the development of EBV-associated tumors....
6.
Van Sciver N, Pulkowski J, Politz S
MicroPubl Biol
. 2020 Jun;
2019.
PMID: 32550407
No abstract available.
7.
Li C, Romero-Masters J, Huebner S, Ohashi M, Hayes M, Bristol J, et al.
PLoS Pathog
. 2020 Jun;
16(6):e1008590.
PMID: 32542010
EBV transforms B cells in vitro and causes human B-cell lymphomas including classical Hodgkin lymphoma (CHL), Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL). The EBV latency protein, EBNA2,...
8.
Romero-Masters J, Huebner S, Ohashi M, Bristol J, Benner B, Barlow E, et al.
PLoS Pathog
. 2020 Feb;
16(2):e1008365.
PMID: 32059024
Humans are infected with two distinct strains (Type 1 (T1) and Type 2 (T2)) of Epstein-Barr virus (EBV) that differ substantially in their EBNA2 and EBNA 3A/B/C latency genes and...
9.
Eichelberg M, Welch R, Guidry J, Ali A, Ohashi M, Makielski K, et al.
mBio
. 2019 Aug;
10(4).
PMID: 31431547
Epstein-Barr virus (EBV) is a human herpesvirus that is associated with lymphomas as well as nasopharyngeal and gastric carcinomas. Although carcinomas account for almost 90% of EBV-associated cancers, progress in...
10.
Weng C, Lee D, Gelbmann C, Van Sciver N, Nawandar D, Kenney S, et al.
J Virol
. 2018 Jun;
92(16).
PMID: 29848590
Human cytomegalovirus (HCMV) productive replication is most often studied in fibroblasts. , fibroblasts amplify viral titers, but transmission and pathogenesis require the infection of other cell types, most notably epithelial...