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Nicholas T Ventham

Explore the profile of Nicholas T Ventham including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 799
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Recent Articles
1.
Chen J, Zhang H, Fu T, Zhao J, Nowak J, Kalla R, et al.
EBioMedicine . 2024 Nov; 110:105443. PMID: 39536393
Background: This study aims to confirm the associations of air pollution with ulcerative colitis (UC) and Crohn's disease (CD); to explore interactions with genetics and lifestyle; and to characterize potential...
2.
Noble A, Adams A, Nowak J, Cheng G, Nayak K, Quinn A, et al.
J Crohns Colitis . 2024 Oct; PMID: 39365013
The genetic contribution to inflammatory bowel disease (IBD) encompassing both Crohn's disease (CD) and ulcerative colitis (UC), accounts for around 20% of disease variance, highlighting the need to characterise environmental...
3.
Zhang H, Kalla R, Chen J, Zhao J, Zhou X, Adams A, et al.
Nat Commun . 2024 Jan; 15(1):595. PMID: 38238335
This work aims to investigate how smoking exerts effect on the development of inflammatory bowel disease (IBD). A prospective cohort study and a Mendelian randomization study are first conducted to...
4.
Ventham N, Kennedy N, Kalla R, Adams A, Noble A, Ennis H, et al.
Cell Mol Gastroenterol Hepatol . 2023 Jun; 16(3):431-450. PMID: 37331566
Background & Aims: DNA methylation alterations may provide important insights into gene-environment interaction in cancer, aging, and complex diseases, such as inflammatory bowel disease (IBD). We aim first to determine...
5.
Shubhakar A, Jansen B, Adams A, Reiding K, Ventham N, Kalla R, et al.
J Crohns Colitis . 2023 Jan; 17(6):919-932. PMID: 36694402
Biomarkers to guide clinical decision making at diagnosis of inflammatory bowel disease [IBD] are urgently needed. We investigated a composite serum N-glycomic biomarker to predict future disease course in a...
6.
Kalla R, Adams A, Nowak J, Bergemalm D, Vatn S, Ventham N, et al.
J Crohns Colitis . 2022 Aug; 17(2):170-184. PMID: 36029471
Background: Epigenetic alterations may provide valuable insights into gene-environment interactions in the pathogenesis of inflammatory bowel disease [IBD]. Methods: Genome-wide methylation was measured from peripheral blood using the Illumina 450k...
7.
Joustra V, Hageman I, Satsangi J, Adams A, Ventham N, de Jonge W, et al.
J Crohns Colitis . 2022 Aug; 17(2):185-198. PMID: 35998097
Background And Aims: Over the past decade, the DNA methylome has been increasingly studied in peripheral blood of inflammatory bowel disease [IBD] patients. However, a comprehensive summary and meta-analysis of...
8.
Leow H, Coupland A, Ventham N
Gastroenterology . 2022 Jul; 163(5):1179-1182. PMID: 35863528
No abstract available.
9.
Gasparetto M, Payne F, Nayak K, Kraiczy J, Glemas C, Philip-McKenzie Y, et al.
Gastroenterology . 2020 Aug; 160(1):232-244.e7. PMID: 32814113
Background & Aims: Gene expression patterns of CD8 T cells have been reported to correlate with clinical outcomes of adults with inflammatory bowel diseases (IBD). We aimed to validate these...
10.
Ventham N, Zanellato A, McKechnie P
Dig Endosc . 2020 Jul; 32(7):1115. PMID: 32705721
No abstract available.