Alex T Adams
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Explore the profile of Alex T Adams including associated specialties, affiliations and a list of published articles.
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15
Citations
255
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Recent Articles
1.
Noble A, Adams A, Satsangi J, Boden J, Osborne A
Mol Psychiatry
. 2024 Sep;
PMID: 39277688
Prenatal cannabis exposure (PCE) is of increasing concern globally, due to the potential impact on offspring neurodevelopment, and its association with childhood and adolescent brain development and cognitive function. However,...
2.
Ventham N, Kennedy N, Kalla R, Adams A, Noble A, Ennis H, et al.
Cell Mol Gastroenterol Hepatol
. 2023 Jun;
16(3):431-450.
PMID: 37331566
Background & Aims: DNA methylation alterations may provide important insights into gene-environment interaction in cancer, aging, and complex diseases, such as inflammatory bowel disease (IBD). We aim first to determine...
3.
Noble A, Nowak J, Adams A, Uhlig H, Satsangi J
Gastroenterology
. 2023 Apr;
165(1):44-60.e2.
PMID: 37062395
Recent advances in our understanding of the pathogenesis of inflammatory bowel disease (IBD) have highlighted the complex interplay between the genome, the epigenome, and the environment. Despite the exciting advances...
4.
Nowak J, Dybska E, Adams A, Walkowiak J
Cent Eur J Immunol
. 2023 Feb;
47(3):246-259.
PMID: 36817262
Introduction: Smoking is known to affect whole-blood expression and methylation profiles. Although whole-genome methylation studies indicated that effects observed in blood may be driven by changes within leukocyte subtypes, these...
5.
Shubhakar A, Jansen B, Adams A, Reiding K, Ventham N, Kalla R, et al.
J Crohns Colitis
. 2023 Jan;
17(6):919-932.
PMID: 36694402
Biomarkers to guide clinical decision making at diagnosis of inflammatory bowel disease [IBD] are urgently needed. We investigated a composite serum N-glycomic biomarker to predict future disease course in a...
6.
Nowak J, Szymanska C, Glapa-Nowak A, Duclaux-Loras R, Dybska E, Ostrowski J, et al.
Genes (Basel)
. 2022 Sep;
13(9).
PMID: 36140740
Although big data from transcriptomic analyses have helped transform our understanding of inflammatory bowel disease (IBD), they remain underexploited. We hypothesized that the application of machine learning using lasso regression...
7.
Kalla R, Adams A, Nowak J, Bergemalm D, Vatn S, Ventham N, et al.
J Crohns Colitis
. 2022 Aug;
17(2):170-184.
PMID: 36029471
Background: Epigenetic alterations may provide valuable insights into gene-environment interactions in the pathogenesis of inflammatory bowel disease [IBD]. Methods: Genome-wide methylation was measured from peripheral blood using the Illumina 450k...
8.
Nowak J, Adams A, Kalla R, Lindstrom J, Vatn S, Bergemalm D, et al.
J Crohns Colitis
. 2022 Feb;
16(8):1255-1268.
PMID: 35212366
Aim: To assess the pathobiological and translational importance of whole-blood transcriptomic analysis in inflammatory bowel disease [IBD]. Methods: We analysed whole-blood expression profiles from paired-end sequencing in a discovery cohort...
9.
Noble A, Purcell R, Adams A, Lam Y, Ring P, Anderson J, et al.
Front Genet
. 2022 Feb;
13:831866.
PMID: 35211161
Epidemiological and associative research from humans and animals identifies correlations between the environment and health impacts. The environment-health inter-relationship is effected through an individual's underlying genetic variation and mediated by...
10.
Bergemalm D, Andersson E, Hultdin J, Eriksson C, Rush S, Kalla R, et al.
Gastroenterology
. 2021 Jul;
161(5):1526-1539.e9.
PMID: 34298022
Background & Aims: Preclinical ulcerative colitis is poorly defined. We aimed to characterize the preclinical systemic inflammation in ulcerative colitis, using a comprehensive set of proteins. Methods: We obtained plasma...