Nicholas M Mellen
Overview
Explore the profile of Nicholas M Mellen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
256
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Jagadapillai R, Mellen N, Sachleben Jr L, Gozal E
PLoS One
. 2014 Jul;
9(7):e100230.
PMID: 25014412
Hypoxia alters cellular metabolism and although the effects of sustained hypoxia (SH) have been extensively studied, less is known about chronic intermittent hypoxia (IH), commonly associated with cardiovascular morbidity and...
2.
Mellen N, Thoby-Brisson M
Curr Opin Neurobiol
. 2012 Jan;
22(4):676-85.
PMID: 22281058
Breathing is a rhythmic motor behavior generated and controlled by hindbrain neuronal networks. Respiratory motor output arises from two distinct, but functionally interacting, rhythmogenic networks: the pre-Bötzinger complex (preBötC) and...
3.
Mellen N, Mishra D
J Neurosci
. 2010 Jun;
30(25):8383-92.
PMID: 20573885
Endogenous burster neurons (EBs) have been found at the level of the facial nucleus (VIIn), and 500 mum caudally, within the pre-Bötzinger complex (preBötC). They have been proposed as either...
4.
Mellen N
Respir Physiol Neurobiol
. 2010 Apr;
172(1-2):1-7.
PMID: 20412870
Recent studies in vivo and in vitro suggest that both respiratory rhythmogenesis and its central chemosensory modulation arise from multiple, mechanistically and/or anatomically distinct networks whose outputs are similar. These...
5.
Mellen N, Tuong C
Neuroimage
. 2009 Apr;
47(4):1331-40.
PMID: 19362155
Bath-applied membrane-permeant Ca(2+) indicators offer access to network function with single-cell resolution. A barrier to wider and more efficient use of this technique is the difficulty of extracting fluorescence signals...
6.
Mellen N
Adv Exp Med Biol
. 2007 Dec;
605:99-103.
PMID: 18085254
Recent studies have shown both the pFRG and the preBötC are sufficient to generate respiratory rhythm, and are hypothesized to do so via distinct mechanisms (Onimaru and Homma 2003; Mellen,...
7.
Mellen N
J Neurosci Methods
. 2007 Nov;
168(1):113-8.
PMID: 17996947
Slice preparations isolate functional networks, permitting single unit recording under visual control, and the use of fluorescent indicators. Circuits of interest often lie at a tilt in both the rostrocaudal...
8.
Barnes B, Tuong C, Mellen N
J Neurophysiol
. 2007 Jan;
97(3):2283-92.
PMID: 17215506
In mammals, respiration-modulated networks are distributed rostrocaudally in the ventrolateral quadrant of the medulla. Recent studies have established that in neonate rodents, two spatially separate networks along this column-the parafacial...
9.
Mellen N, Roham M, Feldman J
J Physiol
. 2004 Feb;
556(Pt 3):859-74.
PMID: 14766932
In mammals, expiration is lengthened by mid-expiratory lung inflation (Breuer-Hering Expiratory reflex; BHE). The central pathway mediating the BHE is paucisynaptic, converging on neurones in the rostral ventrolateral medulla. An...
10.
Mellen N, Janczewski W, Bocchiaro C, Feldman J
Neuron
. 2003 Mar;
37(5):821-6.
PMID: 12628172
Current consensus holds that a single medullary network generates respiratory rhythm in mammals. Pre-Bötzinger Complex inspiratory (I) neurons, isolated in transverse slices, and preinspiratory (pre-I) neurons, found only in more...