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Nicholas J Dunne

Explore the profile of Nicholas J Dunne including associated specialties, affiliations and a list of published articles. Areas
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Articles 51
Citations 599
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Recent Articles
1.
Lin G, Elkashif A, Saha C, Coulter J, Dunne N, McCarthy H
Crit Rev Oncol Hematol . 2025 Feb; 208:104643. PMID: 39900315
Prostate cancer has the second highest cancer mortality rate in the UK in males. Early prostate cancer is typically asymptomatic, with diagnosis at a locally advanced or metastatic stage. In...
2.
Sadat Hashemi T, Jaiswal S, McCarthy H, Levingstone T, Dunne N
Biomater Adv . 2025 Jan; 169:214170. PMID: 39793150
Magnesium (Mg) alloys have gained significant attention as a desirable choice of biodegradable implant for use in bone repair applications, largely owing to their unique material properties. More recently, Mg...
3.
Sutcliffe R, Doherty C, Morgan H, Dunne N, McCarthy H
Biomater Adv . 2024 Dec; 169:214153. PMID: 39705787
Cell-penetrating peptides (CPP) have gained rapid attention over the last 25 years; this is attributed to their versatility, customisation, and 'Trojan horse' delivery that evades the immune system. However, the...
4.
Jiang B, Elkashif A, Coulter J, Dunne N, McCarthy H
Biochim Biophys Acta Rev Cancer . 2024 Jun; 1879(5):189138. PMID: 38889878
Head and neck cancer (HNSCC) is the 8th most common cancer in the UK, with incidence increasing due to lifestyle factors such as tobacco and alcohol abuse. HNSCC is an...
5.
Wilson J, Bennie L, Eguaogie O, Elkashif A, Conlon P, Jena L, et al.
J Control Release . 2024 Mar; 369:63-74. PMID: 38513729
Recent studies in colorectal cancer patients (CRC) have shown that increased resistance to thymidylate synthase (TS) inhibitors such as 5-fluorouracil (5-FU), reduce the efficacy of standard of care (SoC) treatment...
6.
Julius L, Saeed M, Kuijpers T, Sandu S, Henihan G, Dreo T, et al.
ACS Omega . 2024 Jan; 9(3):3262-3275. PMID: 38284094
The ability of the centrifugal Lab-on-a-Disc (LoaD) platform to closely mimic the "on bench" liquid handling steps (laboratory unit operations (LUOs)) such as metering, mixing, and aliquoting supports on-disc automation...
7.
Tzagiollari A, Redmond J, McCarthy H, Levingstone T, Dunne N
Acta Biomater . 2023 Nov; 174:447-462. PMID: 38000527
Phosphoserine is a ubiquitous molecule found in numerous proteins and, when combined with alpha-tricalcium phosphate (α-TCP) powder, demonstrates the ability to generate an adhesive biomaterial capable of stabilising and repairing...
8.
Chambers P, Ziminska M, Elkashif A, Wilson J, Redmond J, Tzagiollari A, et al.
J Control Release . 2023 Sep; 362:489-501. PMID: 37673308
Bone-related injuries and diseases are among the most common causes of morbidity worldwide. Current bone-regenerative strategies such as auto- and allografts are invasive by nature, with adverse effects such as...
9.
McCrudden C, Bennie L, Chambers P, Wilson J, Kerr M, Ziminska M, et al.
J Control Release . 2023 Aug; 362:536-547. PMID: 37648082
Lipid nanoparticles (LNP) have been instrumental in the success of mRNA vaccines and have opened up the field to a new wave of therapeutics. However, what is ahead beyond the...
10.
Sargioti N, Levingstone T, OCearbhaill E, McCarthy H, Dunne N
Bioengineering (Basel) . 2023 Jan; 10(1). PMID: 36671595
Current procedures for transdermal drug delivery (TDD) have associated limitations including poor administration of nucleic acid, small or large drug molecules, pain and stress for needle phobic people. A painless...