Nicholas J Dunne
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Explore the profile of Nicholas J Dunne including associated specialties, affiliations and a list of published articles.
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51
Citations
599
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Recent Articles
11.
Saha C, Bojdo J, Dunne N, Duary R, Buckley N, McCarthy H
Front Bioeng Biotechnol
. 2022 Nov;
10:953887.
PMID: 36420446
High grade serous carcinoma (HGSC) is one of the most lethal ovarian cancers that is characterised by asymptomatic tumour growth, insufficient knowledge of malignant cell origin and sub-optimal detection. HGSC...
12.
Al-Kharusi G, Dunne N, Little S, Levingstone T
Bioengineering (Basel)
. 2022 Oct;
9(10).
PMID: 36290529
Optimisation of tissue engineering (TE) processes requires models that can identify relationships between the parameters to be optimised and predict structural and performance outcomes from both physical and chemical processes....
13.
Redmond J, McCarthy H, Buchanan P, Levingstone T, Dunne N
Biomater Adv
. 2022 Oct;
142:213157.
PMID: 36279748
While 2D culture presents a useful tool for cancer research, it fails to replicate the tumor microenvironment as it lacks proper three-dimensional cell-cell/cell-matrix interactions, often resulting in exaggerated responses to...
14.
Tzagiollari A, McCarthy H, Levingstone T, Dunne N
Bioengineering (Basel)
. 2022 Jun;
9(6).
PMID: 35735493
Bone defects and complex fractures present significant challenges for orthopaedic surgeons. Current surgical procedures involve the reconstruction and mechanical stabilisation of complex fractures using metal hardware (i.e., wires, plates and...
15.
Munir M, Kett V, Dunne N, McCarthy H
Pharm Res
. 2022 Apr;
39(6):1215-1232.
PMID: 35441318
Background: Gene therapy via pulmonary delivery holds the potential to treat various lung pathologies. To date, spray drying has been the most promising method to produce inhalable powders. The present...
16.
Sahebalzamani M, Ziminska M, McCarthy H, Levingstone T, Dunne N, Hamilton A
Biomater Sci
. 2022 Apr;
10(11):2734-2758.
PMID: 35438692
The layer-by-layer (LbL) assembly technique has shown excellent potential in tissue engineering applications. The technique is mainly based on electrostatic attraction and involves the sequential adsorption of oppositely charged electrolyte...
17.
McGivern S, Boutouil H, Al-Kharusi G, Little S, Dunne N, Levingstone T
Bioengineering (Basel)
. 2021 Oct;
8(10).
PMID: 34677217
Cartilage is an avascular tissue with extremely limited self-regeneration capabilities. At present, there are no existing treatments that effectively stop the deterioration of cartilage or reverse its effects; current treatments...
18.
Jena L, Bennie L, McErlean E, Pentlavalli S, Glass K, Burrows J, et al.
J Nanobiotechnology
. 2021 May;
19(1):127.
PMID: 33947409
Glioblastoma multiforme (GBM) is an incurable aggressive brain cancer in which current treatment strategies have demonstrated limited survival benefit. In recent years, nitrogen-containing bisphosphonates (N-BPs) have demonstrated direct anticancer effects...
19.
Redmond J, McCarthy H, Buchanan P, Levingstone T, Dunne N
Mater Sci Eng C Mater Biol Appl
. 2021 Mar;
122:111944.
PMID: 33641930
Collagen is the most abundant component of the extracellular matrix (ECM), therefore it represents an ideal biomaterial for the culture of a variety of cell types. Recently, collagen-based scaffolds have...
20.
McErlean E, McCrudden C, McBride J, Cole G, Kett V, Robson T, et al.
Int J Pharm
. 2021 Jan;
596:120223.
PMID: 33508341
RALA is a cationic amphipathic peptide which has shown great promise as an efficient, multifunctional delivery system for the delivery of nucleic acids. Rational peptide design was utilised in this...