Nicholas G Aboreden
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Explore the profile of Nicholas G Aboreden including associated specialties, affiliations and a list of published articles.
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5
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30
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Recent Articles
1.
Aboreden N, Zhao H, Shan F, Liu F, Zhang H, Blobel G
bioRxiv
. 2025 Feb;
PMID: 39975341
NIPBL promotes chromatin loop extrusion by the cohesin complex until it stalls at convergently oriented CTCF sites, leading to the formation of structural loops. However, to what extent loop extrusion...
2.
Aboreden N, Lam J, Goel V, Wang S, Wang X, Midla S, et al.
Mol Cell
. 2024 Dec;
85(2):376-393.e9.
PMID: 39721581
How specific enhancer-promoter pairing is established remains mostly unclear. Besides the CTCF/cohesin machinery, few nuclear factors have been studied for a direct role in physically connecting regulatory elements. Using a...
3.
Goel V, Aboreden N, Jusuf J, Zhang H, Mori L, Mirny L, et al.
bioRxiv
. 2024 Sep;
PMID: 39345388
As cells exit mitosis and enter G1, mitotic chromosomes decompact and transcription is reestablished. Previously, Hi-C studies showed that essentially all interphase 3D genome features including A/B-compartments, TADs, and CTCF...
4.
Aboreden N, Lam J, Goel V, Wang S, Wang X, Midla S, et al.
bioRxiv
. 2024 Sep;
PMID: 39229045
How specific enhancer-promoter pairing is established is still mostly unclear. Besides the CTCF/cohesin machinery, only a few nuclear factors have been studied for a direct role in physically connecting regulatory...
5.
Lam J, Aboreden N, Midla S, Wang S, Huang A, Keller C, et al.
Nat Genet
. 2024 Aug;
56(9):1938-1952.
PMID: 39210046
Few transcription factors have been examined for their direct roles in physically connecting enhancers and promoters. Here acute degradation of Yin Yang 1 (YY1) in erythroid cells revealed its requirement...
6.
Gryder B, Wachtel M, Chang K, El Demerdash O, Aboreden N, Mohammed W, et al.
iScience
. 2020 May;
23(5):101103.
PMID: 32416589
Core regulatory transcription factors (CR TFs) establish enhancers with logical ordering during embryogenesis and development. Here we report that in fusion-positive rhabdomyosarcoma, a cancer of the muscle lineage, the chief...