Nicholas Barry
Overview
Explore the profile of Nicholas Barry including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
547
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0
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Recent Articles
1.
Zhong Z, Grasso L, Sibilla C, Stevens T, Barry N, Bertolotti A
EMBO J
. 2018 Mar;
37(6).
PMID: 29496740
Protein aggregation is a hallmark of diverse neurodegenerative diseases. Multiple lines of evidence have revealed that protein aggregates can penetrate inside cells and spread like prions. How such aggregates enter...
2.
Das I, Krzyzosiak A, Schneider K, Wrabetz L, DAntonio M, Barry N, et al.
Science
. 2015 Apr;
348(6231):239-42.
PMID: 25859045
Protein phosphorylation regulates virtually all biological processes. Although protein kinases are popular drug targets, targeting protein phosphatases remains a challenge. Here, we describe Sephin1 (selective inhibitor of a holophosphatase), a...
3.
Blaine J, Okamura K, Giral H, Breusegem S, Caldas Y, Millard A, et al.
Am J Physiol Cell Physiol
. 2009 Sep;
297(6):C1339-46.
PMID: 19776390
Parathyroid hormone (PTH) plays a critical role in the regulation of renal phosphorous homeostasis by altering the levels of the sodium-phosphate cotransporter NaPi2a in the brush border membrane (BBM) of...
4.
Giral H, Caldas Y, Sutherland E, Wilson P, Breusegem S, Barry N, et al.
Am J Physiol Renal Physiol
. 2009 Aug;
297(5):F1466-75.
PMID: 19675183
Hyperphosphatemia associated with chronic kidney disease is one of the factors that can promote vascular calcification, and intestinal P(i) absorption is one of the pharmacological targets that prevents it. The...
5.
Levi M, Blaine J, Breusegem S, Takahashi H, Sorribas V, Barry N
Adv Chronic Kidney Dis
. 2006 Apr;
13(2):155-65.
PMID: 16580617
The renal regulation of phosphate is a complex process. Clinical disorders of phosphate handling have led to the identification of several genes and proteins involved in the maintenance of phosphate...
6.
Winn R, Marek L, Han S, Rodriguez K, Rodriguez N, Hammond M, et al.
J Biol Chem
. 2005 Feb;
280(20):19625-34.
PMID: 15705594
The Wnt signaling pathway is critical in normal development, and mutation of specific components is frequently observed in carcinomas of diverse origins. However, the potential involvement of this pathway in...
7.
Masters B, So P, Buehler C, Barry N, Sutin J, Mantulin W, et al.
J Biomed Opt
. 2004 Dec;
9(6):1265-70.
PMID: 15568947
Two-photon excitation fluorescence microscopy allows in vivo high-resolution imaging of human skin structure and biochemistry with a penetration depth over 100 microm. The major damage mechanism during two-photon skin imaging...
8.
Gratton E, Breusegem S, Sutin J, Ruan Q, Barry N
J Biomed Opt
. 2003 Jul;
8(3):381-90.
PMID: 12880343
Fluorescence lifetime images are obtained with the laser scanning microscope using two methods: the time-correlated single-photon counting method and the frequency-domain method. In the same microscope system, we implement both...