Nic D Lindley
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Explore the profile of Nic D Lindley including associated specialties, affiliations and a list of published articles.
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18
Citations
186
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Recent Articles
1.
Chin X, Ho S, Chan G, Basri N, Teo M, Thong A, et al.
J Agric Food Chem
. 2023 Jun;
71(25):9677-9686.
PMID: 37310147
Nontraditional yeasts prevalent in tropical agricultural fermentations such as coffee and cocoa are known to contribute to aroma profiles, yet the functional roles and interactions between the associated microbial consortia...
2.
Bouin A, Zhang C, Lindley N, Truan G, Lautier T
Metab Eng Commun
. 2023 May;
16:e00222.
PMID: 37168436
Fusion of catalytic domains can accelerate cascade reactions by bringing enzymes in close proximity. However, the design of a protein fusion and the choice of a linker are often challenging...
3.
Lautier T, Smith D, Yang L, Chen X, Zhang C, Truan G, et al.
J Agric Food Chem
. 2023 Mar;
71(11):4683-4695.
PMID: 36888893
Cytochromes P450, forming a superfamily of monooxygenases containing heme as a cofactor, show great versatility in substrate specificity. Metabolic engineering can take advantage of this feature to unlock novel metabolic...
4.
Lautier T, Smith D, Yang L, Chen X, Zhang C, Truan G, et al.
Biomolecules
. 2023 Feb;
13(2).
PMID: 36830734
Molecular biodiversity results from branched metabolic pathways driven by enzymatic regioselectivities. An additional complexity occurs in metabolites with an internal structural symmetry, offering identical extremities to the enzymes. For example,...
5.
Daboussi F, Lindley N
Methods Mol Biol
. 2022 Oct;
2553:1-20.
PMID: 36227536
Metabolic engineering has evolved towards creating cell factories with increasingly complex pathways as economic criteria push biotechnology to higher value products to provide a sustainable source of speciality chemicals. Optimization...
6.
Zhang C, Chen X, Lindley N, Too H
Biotechnol Bioeng
. 2017 Oct;
115(1):174-183.
PMID: 29077207
Apocarotenoids, such as α-, β-ionone, and retinol, have high commercial values in the food and cosmetic industries. The demand for natural ingredients has been increasing dramatically in recent years. However,...
7.
Izac M, Garnier D, Speck D, Lindley N
PLoS One
. 2015 Dec;
10(12):e0145251.
PMID: 26684737
It has been claimed that citrate synthase, aconitase and isocitrate dehydrogenase activities are non-functional in Bordetella pertussis and that this might explain why this bacterium's growth is sometimes associated with...
8.
Botella L, Lindley N, Eggeling L
J Bacteriol
. 2009 Feb;
191(8):2899-901.
PMID: 19233926
Genome sequence information suggests that B(12)-dependent mutases are present in a number of bacteria, including members of the suborder Corynebacterineae like Mycobacterium tuberculosis and Corynebacterium glutamicum. We here functionally identify...
9.
Rodriguez-Prados J, de Atauri P, Maury J, Ortega F, Portais J, Chassagnole C, et al.
Biotechnol Bioeng
. 2009 Feb;
103(3):609-20.
PMID: 19219914
Genetic engineering of metabolic pathways is a standard strategy to increase the production of metabolites of economic interest. However, such flux increases could very likely lead to undesirable changes in...
10.
Nicolas C, Kiefer P, Letisse F, Kromer J, Massou S, Soucaille P, et al.
FEBS Lett
. 2007 Jul;
581(20):3771-6.
PMID: 17631881
The deletion of the zwf gene encoding G6PDH activity led to restructuring of the carbon flux through central metabolism in Escherichia coli, though over-expression of this gene had only minor...