Nesri Padayatchi
Overview
Explore the profile of Nesri Padayatchi including associated specialties, affiliations and a list of published articles.
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Articles
111
Citations
3365
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Recent Articles
1.
Garcia-Prats A, Garcia-Cremades M, Cox V, Kredo T, Dunbar R, Schaaf H, et al.
Lancet Child Adolesc Health
. 2025 Jan;
9(2):100-111.
PMID: 39855750
Background: There are few data on the treatment of children and adolescents with multidrug-resistant (MDR) or rifampicin-resistant (RR) tuberculosis, especially with more recently available drugs and regimens. We aimed to...
2.
Nimmo C, Ortiz A, Tan C, Pang J, Acman M, Millard J, et al.
Genome Med
. 2024 Feb;
16(1):34.
PMID: 38374151
Background: Drug resistance in tuberculosis (TB) poses a major ongoing challenge to public health. The recent inclusion of bedaquiline into TB drug regimens has improved treatment outcomes, but this advance...
3.
Reis K, Wolf A, Perumal R, Seepamore B, Guzman K, Ross J, et al.
J Acquir Immune Defic Syndr
. 2024 Feb;
PMID: 38323838
Introduction: For people living with HIV/AIDS, care is commonly delivered through Differentiated Service Delivery (DSD). Although people with multidrug-resistant tuberculosis (MDR-TB) and HIV/AIDS experience severe treatment associated challenges, there is...
4.
Perumal R, Bionghi N, Nimmo C, Letsoalo M, Cummings M, Hopson M, et al.
Eur Respir J
. 2023 Nov;
62(6).
PMID: 37945030
No abstract available.
5.
Maseko T, Ngubane S, Letsoalo M, Rambaran S, Archary D, Samsunder N, et al.
BMC Immunol
. 2023 Aug;
24(1):26.
PMID: 37653422
Background: Lung cavitation is associated with heightened TB transmission and poor treatment outcomes. This study aimed to determine the relationship between systemic inflammation and lung cavitation in drug-resistant TB patients...
6.
Lale Ngema S, Dookie N, Perumal R, Nandlal L, Naicker N, Letsoalo M, et al.
J Clin Tuberc Other Mycobact Dis
. 2023 Aug;
33:100387.
PMID: 37554582
Background: High-dose isoniazid is recommended in the 9-12 months short-course regimen for multidrug-resistant tuberculosis with mutation. However, there is insufficient evidence to support the assumption of genotypic-phenotypic concordance. This study...
7.
Rambaran S, Maseko T, Lewis L, Hassan-Moosa R, Archary D, Ngcapu S, et al.
BMC Immunol
. 2023 Jul;
24(1):21.
PMID: 37480005
Background: Understanding the complex interactions of the immune response mediated by Mycobacterium tuberculosis and HIV co-infection is fundamental to disease biomarker discovery, vaccine, and drug development. Using flow cytometry, we...
8.
Maseko T, Rambaran S, Ngubane S, Lewis L, Ngcapu S, Hassan-Moosa R, et al.
Sci Rep
. 2023 Jul;
13(1):11726.
PMID: 37474556
Natural killer (NK) cells, key effector cells of the innate immune system, play an important role in the clearance and control of Mycobacterium tuberculosis and HIV infections. Here, we utilized...
9.
Perumal R, Khan A, Naidoo K, Ngema S, Nandlal L, Padayatchi N, et al.
Infect Drug Resist
. 2023 May;
16:2849-2859.
PMID: 37193296
Background: Understanding () intra-host evolution of drug resistance is important for successful drug-resistant tuberculosis (DR-TB) treatment and control strategies. This study aimed to characterise the acquisition of genetic mutations and...
10.
Perumal R, Naidoo K, Naidoo A, Letsoalo M, Esmail A, Joubert I, et al.
Int J Infect Dis
. 2022 Dec;
126:174-180.
PMID: 36462574
Objectives: Critically ill patients with tuberculosis (TB) face a high mortality risk and require effective treatment. There is a paucity of data on rifampicin pharmacokinetics, the impact of continuous enteral...